Clinical data
AHFS/ International Drug Names
ATC code C09AA12 (WHO)
CAS Number 83435-66-9 YesY
PubChem (CID) 5362116
ChemSpider 4514931 N
KEGG D07781 YesY
Chemical and physical data
Formula C26H32N2O5
Molar mass 452.542 g/mol
3D model (Jmol) Interactive image
 NYesY (what is this?)  (verify)

Delapril (INN, also known as alindapril) is an ACE inhibitor used as an antihypertensive drug[1] in some European and Asian countries but not in America.[2] It is taken orally, available in 15mg and 30mg tablets.[3]


Delapril is a prodrug; it is converted into two active metabolites, 5-hydroxy delapril diacid and delapril diacid. These metabolites bind completely to and inhibit angiotensin-converting enzyme (ACE), hence blocking angiotensin I to angiotensin II conversion. The resulting vasodilation prevents the vasoconstrictive effects of angiotensin II. Angiotensin II-induced aldosterone secretion by the adrenal cortex is also decreased by Delapril, leading to increases in excretion of sodium and therefore increases water outflow.[4]


  1. Otero, M. L. (2007). "Manidipine-delapril combination in the management of hypertension". Vascular health and risk management. 3 (3): 255–263. PMC 2293964Freely accessible. PMID 17703633.
  2. Delapril
  3. "". Retrieved 2016-08-28. External link in |title= (help)
  4. Pubchem. "DELAPRIL | C26H32N2O5 - PubChem". Retrieved 2016-08-28.
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