|Amlodipine||Calcium channel blocker|
|Valsartan||Angiotensin II receptor antagonist|
|ATC code||C09DB01 (WHO)|
Amlodipine/valsartan is of an oral blood pressure lowering combination drug which combines two medications in a film-coated tablet. It contains amlodipine, a dihydropyridine-type calcium channel blocker, and valsartan, an angiotensin II receptor antagonist (ARB or A2RA); typically formulated as the benzenesulfonate salt. Meta-analysis has shown this combination to be well tolerated and effective for the reduction of blood pressure.
Amlodipine/valsartan is available in different dose preparations: 5 mg/80 mg, 5 mg/160 mg, 10 mg/160 mg, 5 mg/320 mg and 10/320 mg of amlodipine and valsartan, respectively.
The combination is also available with included hydrochlorothiazide, for patients who need a three drug regimen to manage their blood pressure.
- Eckert, Siegfried; Freytag, Siegfried B.; Müller, Alfons; Klebs, Sven H. G. (2013). "Meta-analysis of three observational studies of amlodipine/valsartan in hypertensive patients with additional risk factors". Blood Pressure. 22 (sup1): 11–21. doi:10.3109/08037051.2013.793891. ISSN 0803-7051.
- "Generic Exforge HCT". Blood-pressure.emedtv.com. Retrieved 2012-03-05.