Alpha-guaiene synthase

Alpha-guaiene synthase
Identifiers
EC number 4.2.3.87
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Alpha-guaiene synthase (EC 4.2.3.87, PatTps177 (gene)) is an enzyme with systematic name (2Z,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, alpha-guaiene-forming).[1][2] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate alpha-guaiene + diphosphate

This enzyme requires Mg2+.

References

  1. Deguerry, F.; Pastore, L.; Wu, S.; Clark, A.; Chappell, J.; Schalk, M. (2006). "The diverse sesquiterpene profile of patchouli, Pogostemon cablin, is correlated with a limited number of sesquiterpene synthases". Arch. Biochem. Biophys. 454: 123–136. doi:10.1016/j.abb.2006.08.006. PMID 16970904.
  2. Kumeta, Y.; Ito, M. (2010). "Characterization of δ-guaiene synthases from cultured cells of Aquilaria, responsible for the formation of the sesquiterpenes in agarwood". Plant Physiol. 154 (4): 1998–2007. doi:10.1104/pp.110.161828. PMID 20959422.

External links

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