Sulfoacetaldehyde dehydrogenase (acylating)

Sulfoacetaldehyde dehydrogenase (acylating)
Identifiers
EC number 1.2.1.81
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Sulfoacetaldehyde dehydrogenase (acylating) (EC 1.2.1.81, SauS) is an enzyme with systematic name 2-sulfoacetaldehyde:NADP+ oxidoreductase (CoA-acetylating).[1] This enzyme catalyses the following chemical reaction

2-sulfoacetaldehyde + CoA + NADP+ sulfoacetyl-CoA + NADPH + H+

The enzyme is involved in degradation of sulfoacetate.

References

  1. Weinitschke, S.; Hollemeyer, K.; Kusian, B.; Bowien, B.; Smits, T.H.; Cook, A.M. (2010). "Sulfoacetate is degraded via a novel pathway involving sulfoacetyl-CoA and sulfoacetaldehyde in Cupriavidus necator H16". J. Biol. Chem. 285 (46): 35249–35254. doi:10.1074/jbc.M110.127043. PMC 2975148Freely accessible. PMID 20693281.
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