Jonathan O'Neal Kirksey (born February 21, 1970 in Greenville, South Carolina) is a former professional American football defensive tackle in the National Football League and NFL Europe League. In his six-year pro career he played for the St. Louis Rams of the NFL and the Amsterdam Admirals of NFL Europe. Kirksey played college football at Bakersfield College and Sacramento State.
Kirksey was selected by the New Orleans Saints in the eighth round (221st overall) of the 1993 NFL Draft. He was waived on August 24, 1993.