Wellcome Trust Centre for Cell-Matrix Research

The Wellcome Trust Centre for Cell-Matrix Research at the University of Manchester pursues advances in the understanding of extracellular matrix (ECM) biology and its contribution to human diseases. The Centre was established in 1995 and Professor Charles Streuli is the Centre's Director.

A key aim for the Centre is to clarify the roles of adhesion molecules, found on the exterior of cells and how they bind to and organise the ECM. These interactions ultimately affect cell behaviour and are of importance medically: defects in cell-ECM interactions underpin many diseases, including cancer, diabetes, heart disease, osteoarthritis, inflammatory disorders, some forms of blindness, and many genetically inherited conditions.

The Centre focuses on cellular matrix microenvironment, matrix immunobiology, and mechanobiology of the matrix.[1]

See also


  1. "Wellcome Trust Centre for Wellcome Trust Centre for Cell-Matrix Research" (PDF). University of Manchester. 2014. Retrieved 22 October 2016.

External links

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