Uterotonic

A uterotonic, also known as ecbolic, is an agent used to induce contraction or greater tonicity of the uterus. Uterotonics are used both to induce labor, and to reduce postpartum hemorrhage.

Some uterotonics act as analogues of oxytocin. An oxytocinergic, or oxytocic, means "having to do with oxytocin (OXT)". The oxytocin receptor (OXTR) is the binding and activation site of oxytocin.

Some agents may act as indirect oxytocinergics:

Prostaglandins
Analogs of oxytocin
Tocolytic

See also

References

  1. Nagashima, Renpei; Takano, Noboru; Tamura, Masaaki; Shioya, Akitoshi (1966). "PHARMACOLOGICAL PROPERTIES OF 3-(p-CHLOROBENZYL) QUINOLIZIDINE TARTARATE (QB-1), A NEW OXYTOCIC". The Japanese Journal of Pharmacology. 16 (4): 353–367. doi:10.1254/jjp.16.353. ISSN 0021-5198.
  2. Elks, J.; Ganellin, C. R. (1990). "Dictionary of Drugs". doi:10.1007/978-1-4757-2085-3. ISBN 978-1-4757-2087-7.
  3. https://www.openanesthesia.org/aba_oxytocic_drugs_-_indications/
  4. Garcia-Villar, R.; Marnet, P.G.; Laurentie, M.P.; Toutain, P.L. (1987). "Fenprostalene in cattle: Evaluation of oxytocic effects in ovariectomized cows and abortion potential in a 100-day pregnant cow". Theriogenology. 28 (4): 467–480. doi:10.1016/0093-691X(87)90251-2. ISSN 0093-691X.
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