Tropane alkaloid

The chemical structure of tropane

Tropane alkaloids are a class of bicyclic [3.2.1] alkaloids and secondary metabolites that contain a tropane ring in their chemical structure.[1] Tropane alkaloids occur naturally in many members of the plant family Solanaceae. Some tropane alkaloids have pharmacological properties and can act as anticholinergics or stimulants.


Anticholinergic drugs[2] and deliriants:

All three acetylcholine-inhibiting chemicals can also be found in the leaves, stems, and flowers in varying, unknown amounts in Brugmansia (angel trumpets or devil's weed), a relative of Datura.


Stimulants and cocaine-related alkaloids:


Non-natural tropanes

There exist some synthetic analogs of tropane alkaloids, see

They are not considered to be alkaloids per definition.

See also


  1. O’Hagan, David (2000). "Pyrrole, pyrrolidine, pyridine, piperidine and tropane alkaloids (1998 to 1999)". Natural Product Reports. 17 (5): 435–446. doi:10.1039/a707613d.
  2. Grynkiewicz, G; Gadzikowska, M. "Tropane alkaloids as medicinally useful natural products and their synthetic derivatives as new drugs.". Pharmacological reports : PR. 60 (4): 439–63. PMID 18799813.
This article is issued from Wikipedia - version of the 11/7/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.