Trimerelysin II
| Trimerelysin II | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.4.24.53 | ||||||||
| CAS number | 151125-15-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Trimerelysin II (EC 3.4.24.53, Trimeresurus metalloendopeptidase II, proteinase H2, H2-proteinase) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction
- Cleavage of Asn3-Gln, His10-Leu and Ala14-Leu in the insulin B chain, and the bond Z-Gly-Pro-Leu-Gly-Pro in a small molecule substrate of microbial collagenase
This endopeptidase is present in the venom of the habu snake (Trimeresurus flavoviridis).
References
- ↑ Takahashi, T.; Ohsaka, A. (1970). "Purification and characterization of a proteinase in the venom of Trimeresurus flavoviridis. Complete separation of the enzyme from hemorrhagic activity". Biochim. Biophys. Acta. 198: 293–307. doi:10.1016/0005-2744(70)90062-8. PMID 4984550.
- ↑ Takeya, H.; Arakawa, M.; Miyata, T.; Iwanaga, S.; Omori-Satoh, T. (1989). "Primary structure of H2-proteinase, a non-hemorrhagic metalloproteinase, isolated from the venom of the habu snake, Trimeresurus flavoviridis". J. Biochem. (Tokyo). 106: 151–157. PMID 2777746.
External links
- Trimerelysin II at the US National Library of Medicine Medical Subject Headings (MeSH)
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