Clinical data
Trade names Topiloric, Uriadec
ATC code None
Legal status
Legal status
  • Approved in Japan
CAS Number 577778-58-6
PubChem (CID) 5288320
ChemSpider 4450517
Chemical and physical data
Formula C13H8N6
Molar mass 248.24 g/mol
3D model (Jmol) Interactive image

Topiroxostat (INN; trade names Topiloric, Uriadec) is a drug for the treatment of gout and hyperuricemia.[1] It was approved for use in Japan in June 2013.[1]

Topiroxostat is a xanthine oxidase inhibitor which reduces serum urate levels.[2]


  1. 1 2 "New Drugs FY2013" (PDF). Pharmaceuticals and Medical Devices Agency, Japan.
  2. Hosoya, Tatsuo; Ohno, Iwao; Nomura, Shinsuke; Hisatome, Ichiro; Uchida, Shunya; Fujimori, Shin; Yamamoto, Tetsuya; Hara, Shigeko (2014). "Effects of topiroxostat on the serum urate levels and urinary albumin excretion in hyperuricemic stage 3 chronic kidney disease patients with or without gout". Clinical and Experimental Nephrology. doi:10.1007/s10157-014-0935-8.

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