Clinical data
ATC code G04BD05 (WHO)
PubChem (CID) 23480
ChemSpider 21952 YesY
UNII 70KG06964W YesY
Chemical and physical data
Formula C20H27N
Molar mass 281.435 g/mol
3D model (Jmol) Interactive image

Terodiline is a drug used in urology as an antispasmodic.

It relaxes the smooth muscle and used to reduce bladder tone in treatment of urinary frequency and incontinence. Muscle relaxation caused by terodiline, is probably due to its anticholinergic and calcium antagonist activity.

However, it also blocks IKr (Kv11.1) channels (see hERG gene) so can pose a risk for torsades de pointes. This cardiotoxicity is concentration dependent.[1]


  1. Thomas SH, Higham PD, Hartigan-Go K, Kamali F, Wood P, Campbell RW, Ford GA. "Concentration dependent cardiotoxicity of terodiline in patients treated for urinary incontinence".

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