Telogen effluvium

Telogen effluvium
An Afghan child displaying hair loss due to severe malnutrition.
Classification and external resources
Specialty dermatology
ICD-10 L65.0 (ILDS L65.000)
ICD-9-CM 704.02
DiseasesDB 12926

Telogen effluvium is a scalp disorder characterized by the thinning or shedding of hair resulting from the early entry of hair in the telogen phase (the resting phase of the hair follicle).[1][2] Emotional or physiological stress may result in an alteration of the normal hair cycle and cause the disorder, with potential etiologies including eating disorders, fever, childbirth, chronic illness, major surgery, anemia, severe emotional disorders, crash diets, hypothyroidism, and drugs.[1][3]

Diagnostic tests, which may be performed to verify the diagnosis, include a trichogram, trichoscopy[4] and biopsy.[3] Effluvium can present with similar appearance to alopecia totalis, with further distinction by clinical course, microscopic examination of plucked follicles, or biopsy of the scalp.[5] Histology would show telogen hair follicles in the dermis with minimal inflammation in effluvium, and dense peribulbar lymphocytic infiltrate in alopecia totalis.[6]

Vitamin D levels may also play a role in normal hair cycle.[7]

See also

References

  1. 1 2 Marks, James G; Miller, Jeffery (2006). Lookingbill and Marks' Principles of Dermatology (4th ed.). Elsevier Inc. Page 263. ISBN 1-4160-3185-5.
  2. James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.
  3. 1 2 Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0-07-138076-0.
  4. Rudnicka L, Olszewska M, Rakowska A, Kowalska-Oledzka E, Slowinska M (2008). "Trichoscopy: a new method for diagnosing hair loss". J Drugs Dermatol. 7 (7): 651–654. PMID 18664157.
  5. Werner, B.; Mulinari-Brenner, F. (2012). "Clinical and histological challenge in the differential diagnosis of diffuse alopecia: Female androgenetic alopecia, telogen effluvium and alopecia areata - part II". Anais brasileiros de dermatologia. 87 (6): 884–890. PMID 23197208.
  6. Alkhalifah, A. (2012). "Alopecia Areata Update". Dermatologic Clinics. 31 (1): 93–108. doi:10.1016/j.det.2012.08.010. PMID 23159179.
  7. Does D matter? The role of vitamin D in hair disorders and hair follicle cycling. Dermatol Online J. 2010 Feb; 16(2). PMID 20178699
This article is issued from Wikipedia - version of the 8/3/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.