In dermatology, a target lesion or bull's-eye lesion, named for its resemblance to the bull's-eye of a shooting target, is the typical lesion of erythema multiforme (EM) in which a vesicle is surrounded by an often hemorrhagic maculopapule; EM is often self-limited, of acute onset, resolves in three to six weeks, and has a cyclical pattern; EM lesions are multiform (polymorphous) and include macules, papules, vesicles, and bullae. Target lesions are also typical of erythema chronicum migrans.
Target lesion consists of three zones :
- Dark centre of small papule, vesicle, or bulla (iris)
- Pale intermediate zone
- Peripheral rim of erythema