TSHZ1
Template:PBB/10194
Teashirt zinc finger homeobox 1 is a protein that in humans is encoded by the TSHZ1 gene. [1]
Function
This gene encodes a colon cancer antigen that was defined by serological analysis of recombinant cDNA expression libraries. The encoded protein is a member of the teashirt C2H2-type zinc-finger protein family and may be involved in transcriptional regulation of developmental processes. Mutations in this gene may be associated with congenital aural atresia syndrome. [provided by RefSeq, Jan 2012]. ##Evidence-Data-START## Transcript exon combination :: DB284179.1, AL833321.1 [ECO:0000332] RNAseq introns :: single sample supports all introns ERS025081, ERS025082 [ECO:0000348] ##Evidence-Data-END##
References
- ↑ "Entrez Gene: Teashirt zinc finger homeobox 1". Retrieved 2013-11-28.
Further reading
- Schick, B.; Wemmert, S.; Willnecker, V.; Dlugaiczyk, J.; Nicolai, P.; Siwiec, H.; Thiel, C. T.; Rauch, A.; Wendler, O. (2011). "Genome-wide copy number profiling using a 100K SNP array reveals novel disease-related genes BORIS and TSHZ1 in juvenile angiofibroma". International Journal of Oncology. 39 (5): 1143–1151. doi:10.3892/ijo.2011.1166. PMID 21874228.
- Kajiwara, Y.; Akram, A.; Katsel, P.; Haroutunian, V.; Schmeidler, J.; Beecham, G.; Haines, J. L.; Pericak-Vance, M. A.; Buxbaum, J. D. (2009). Bush, Ashley I, ed. "FE65 Binds Teashirt, Inhibiting Expression of the Primate-Specific Caspase-4". PLoS ONE. 4 (4): e5071. doi:10.1371/journal.pone.0005071. PMC 2660419
. PMID 19343227. - Scanlan, M. J.; Chen, Y. T.; Williamson, B.; Gure, A. O.; Stockert, E.; Gordan, J. D.; Türeci, Ö.; Sahin, U.; Pfreundschuh, M.; Old, L. J. (1998). "Characterization of human colon cancer antigens recognized by autologous antibodies". International Journal of Cancer. 76 (5): 652–658. doi:10.1002/(SICI)1097-0215(19980529)76:5<652::AID-IJC7>3.0.CO;2-P. PMID 9610721.
- Coré, N.; Caubit, X.; Metchat, A. C.; Boned, A.; Djabali, M.; Fasano, L. (2007). "Tshz1 is required for axial skeleton, soft palate and middle ear development in mice". Developmental Biology. 308 (2): 407–420. doi:10.1016/j.ydbio.2007.05.038. PMID 17586487.
- Feenstra, I.; Vissers, L. E. L. M.; Pennings, R. J. E.; Nillessen, W.; Pfundt, R.; Kunst, H. P.; Admiraal, R. J.; Veltman, J. A.; Van Ravenswaaij-Arts, C. M. A.; Brunner, H. G.; Cremers, C. W. R. J. (2011). "Disruption of Teashirt Zinc Finger Homeobox 1 is Associated with Congenital Aural Atresia in Humans". The American Journal of Human Genetics. 89 (6): 813–819. doi:10.1016/j.ajhg.2011.11.008. PMC 3234381. PMID 22152683.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.