TNPO2

TNPO2
Identifiers
Aliases TNPO2, IPO3, KPNB2B, TRN2, transportin 2
External IDs MGI: 2384849 HomoloGene: 8381 GeneCards: TNPO2
RNA expression pattern




More reference expression data
Orthologs
Species Human Mouse
Entrez

30000

212999

Ensembl

ENSG00000105576

ENSMUSG00000031691

UniProt

O14787

Q99LG2

RefSeq (mRNA)

NM_013433
NM_001136195
NM_001136196

NM_001122843
NM_145390

RefSeq (protein)

NP_001129667.1
NP_001129668.1
NP_038461.2
NP_001129667.1
NP_038461.2

NP_001116315.1
NP_663365.3

Location (UCSC) Chr 19: 12.7 – 12.72 Mb Chr 8: 85.04 – 85.06 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Transportin-2 is a protein that in humans is encoded by the TNPO2 gene.[3][4][5]

Interactions

TNPO2 has been shown to interact with NXF1,[4] NUP98[6] and Ran (biology).[4]

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Siomi MC, Eder PS, Kataoka N, Wan L, Liu Q, Dreyfuss G (October 1997). "Transportin-mediated nuclear import of heterogeneous nuclear RNP proteins". J Cell Biol. 138 (6): 1181–92. doi:10.1083/jcb.138.6.1181. PMC 2132560Freely accessible. PMID 9298975.
  4. 1 2 3 Shamsher MK, Ploski J, Radu A (October 2002). "Karyopherin beta 2B participates in mRNA export from the nucleus". Proc Natl Acad Sci U S A. 99 (22): 14195–9. doi:10.1073/pnas.212518199. PMC 137860Freely accessible. PMID 12384575.
  5. "Entrez Gene: TNPO2 transportin 2 (importin 3, karyopherin beta 2b)".
  6. Fontoura, B M; Blobel G; Yaseen N R (October 2000). "The nucleoporin Nup98 is a site for GDP/GTP exchange on ran and termination of karyopherin beta 2-mediated nuclear import". J. Biol. Chem. UNITED STATES. 275 (40): 31289–96. doi:10.1074/jbc.M004651200. ISSN 0021-9258. PMID 10875935.

Further reading


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