Susan M. Gasser

Susan M. Gasser is a professor of molecular biology at the University of Basel. She is currently the director of Friedrich Miescher Institute for Biomedical Research since November 2004.[1]

Early career

Susan Gasser received her doctorate at the University of Basel in Biochemistry for the development of an in vitro system for the import of mitochondrial proteins with Gottfried (Jeff) Schatz. She studied the long-range folding of the genome in flies and human cells as a post-doctoral fellow at the University of Geneva with Ulrich K. Laemmli .[1][2]


Gasser presently holds a professorship at the University of Basel and runs a research laboratory at the FMI as well as leading the institute. From 1986 to 2001, Gasser led a research group at the Swiss Institute for Experimental Cancer Research. She discovered and documented the clustering of yeast telomeres at the nuclear envelope, and elucidated the role of this subnuclear distribution in heritable gene repression using a combined genetic and fluorescence microscopy approach. From 2001 to 2004, Gasser was a professor of Molecular Biology at the University of Geneva. Since 2004, she is the Director of the Friedrich Miescher Institute in Basel, and Professor of Molecular Biology at the University of Basel. Gasser has served on review boards and advisory councils throughout Switzerland and Europe.[2][1][3]

Career history


Selected publications

  1. 2013 TORC2 signaling pathway guarantees genome stability in face of DNA strand breaks. Mol Cell, 51:829-839, Shimada K, Fillipuzzi I, Stahl M, Helliwell SB, Seeber A, Loewith R, Movva R, Gasser SM[6]
  2. 2013 The shelterin protein POT-1 anchors C. elegans telomeres through SUN-1 at the nuclear periphery. J Cell Biol, 203:727-35, Ferreira HC, Towbin BD, Jegou T, Gasser SM[6]
  3. 2013 Checkpoint kinases and nucleosome remodelers enhance global chromatin mobility in response to DNA damage. Genes Dev, 27:1999-2008. doi:10.1101/gad.222992.113, Seeber A, Dion V, Gasser SM [6]
  4. 2013 Cohesin and the nucleolus constrain the mobility of spontaneous repair foci. EMBO Rep. 14:984-991, Dion V, Kalck V, Seeber A, Schleker T, Gasser SM[6]
  5. 2013 SIR proteins and the assembly of silent chromatin in budding yeast. Annu Rev Genet. 47:275-306, Kueng S, Oppikofer M, Gasser SM [6]
  6. 2013 Dimerization of Sir3 via its C-terminal winged helix domain is essential for yeast heterochromatin formation. EMBO J. 32:437-449, Oppikofer M, Kueng S, Keusch JJ, Hassler M, Ladurner A, Gut H, Gasser SM [6]
  7. 2013 Promoter- and RNA polymerase II-dependent hsp-16 gene association with nuclear pores in Caenorhabditis elegans. J Cell Biol, 200:589-604 SMG is corresponding author, Rohner S, Kalck V, Wang FF, Ikegami K, Lieb JD, Gasser SM, Meister P [6]
  8. 2012 Step-wise methylation of histone H3K9 positions chromosome arms at the nuclear periphery in C. elegans embryos. Cell, 150:934-947, Towbin BD, Gonzalez-Aguilera C, Sack R, Gaidatzis D, Kalck V, Meister P, Askjaer P, Gasser SM [6]
  9. 2012 Increased dynamics of double strand breaks requires Mec1, Rad9 and the homologous recombination machinery. Nat Cell Biol. 14:502-509, Dion V, Kalck V, Horigome C, Towbin BD, Gasser SM[6]
  10. 2012 Targeted INO80 enhances subnuclear chromatin movement and ectopic homologous recombination. Genes Dev 26:369-383, Neumann FR, Dion V, Gehlen L, Tsai-Pflugfelder M, Schmid R, Taddei A, Gasser SM[6]

Notes and references

External links

This article is issued from Wikipedia - version of the 9/25/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.