Sulfur mustard

Sulfur mustard
Preferred IUPAC name
Other names
Bis(2-chloroethyl) sulfide
Mustard gas
Yellow cross liquid
Distilled mustard
Mustard T- mixture
Dichlorodiethyl sulfide
505-60-2 YesY
3D model (Jmol) Interactive image
ChEBI CHEBI:25434 YesY
ChEMBL ChEMBL455341 YesY
ChemSpider 21106142 YesY
ECHA InfoCard 100.209.973
KEGG C19164 YesY
PubChem 10461
Molar mass 159.07 g·mol−1
Appearance Colorless if pure. Normally ranges from pale yellow to dark brown. Slight garlic or horseradish type odor.[1]
Density 1.27 g/mL, liquid
Melting point 14.4 °C (57.9 °F; 287.5 K)
Boiling point 217 °C (423 °F; 490 K) begins to decompose at 217 °C (423 °F) and boils at 218 °C (424 °F)
Solubility soluble in ether, benzene, lipids, alcohol, THF
Main hazards Poison, contact hazard, inhalation hazard, corrosive, environmental hazard, carcinogenic, possibly mutagenic
Safety data sheet External MSDS
Very toxic (T+)
Dangerous for the environment (N)
Carc. Cat 1
NFPA 704
Flammability code 1: Must be pre-heated before ignition can occur. Flash point over 93 °C (200 °F). E.g., canola oil Health code 4: Very short exposure could cause death or major residual injury. E.g., VX gas Reactivity code 1: Normally stable, but can become unstable at elevated temperatures and pressures. E.g., calcium Special hazards (white): no codeNFPA 704 four-colored diamond
Flash point 105 °C (221 °F; 378 K)
Related compounds
Related compounds
Nitrogen mustard, Bis(chloroethyl) ether
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

Sulfur mustard, commonly known as mustard gas, is a cytotoxic and vesicant chemical warfare agent with the ability to form large blisters on exposed skin and in the lungs.[2] Related chemical compounds with similar chemical structure and similar properties form a class of compounds known collectively as sulfur mustards or mustard agents. Pure sulfur mustards are colorless, viscous liquids at room temperature. When used in impure form, such as warfare agents, they are usually yellow-brown in color and have an odor resembling mustard plants, garlic, or horseradish, hence the name. Sulfur mustard was originally assigned the name LOST, after the scientists Wilhelm Lommel and Wilhelm Steinkopf, who developed a method of large-scale production for the Imperial German Army in 1916.[3]

Mustard agents are regulated under the 1993 Chemical Weapons Convention (C.W.C.). Three classes of chemicals are monitored under this Convention, with sulfur and nitrogen mustard grouped in Schedule 1, as substances with no use other than in chemical warfare. Mustard agents could be deployed on the battlefield by means of artillery shells, aerial bombs, rockets, or by spraying from warplanes.


Sulfur mustard is the organic compound with formula (ClCH2CH2)2S. In the Depretz method, sulfur mustard is synthesized by treating sulfur dichloride with ethylene:

SCl2 + 2 C2H4 → (ClCH2CH2)2S

In the Levinstein process, disulfur dichloride is used instead:[4][5]

8 S2Cl2 + 16 C2H4 → 8 (ClCH2CH2)2S + S8

In the Meyer method, thiodiglycol is produced from chloroethanol and potassium sulfide and chlorinated with phosphorus trichloride:[6]

3 (HOCH2CH2)2S + 2 PCl3 → 3 (ClCH2CH2)2S + 2 P(OH)3

In the Meyer-Clarke method, concentrated hydrochloric acid (HCl) instead of PCl3 is used as the chlorinating agent:

(HOCH2CH2)2S + 2 HCl → (ClCH2CH2)2S + 2 H2O

Thionyl chloride and phosgene, the latter of which (CG) is also a choking agent, have also been used as chlorinating agents.

Sulfur mustard is a viscous liquid at normal temperatures. The pure compound has a melting point of 14 °C (57 °F) and decomposes before boiling at 218 °C (424 °F).

Mechanism of cellular toxicity

The compound readily eliminates a chloride ion by intramolecular nucleophilic substitution to form a cyclic sulfonium ion. This very reactive intermediate tends to cause permanent alkylation of the guanine nucleotide in DNA strands, which prevents cellular division and generally leads directly to programmed cell death,[7] or, if cell death is not immediate, the damaged DNA may lead to the development of cancer.[7] Oxidative stress would be another pathology involved in sulfur mustard toxicity. Sulfur mustard is not very soluble in water but is very soluble in fat, contributing to its rapid absorption into the skin.[7]

Mustard gas (bis(chloroethyl) thioether) alkylating a DNA amine base

In the wider sense, compounds with the structural element BCH2CH2X, where X is any leaving group, and B is a Lewis base are known as mustards. Such compounds can form cyclic "onium" ions (sulfonium, ammoniums, etc.) that are good alkylating agents. Examples are bis(2-chloroethyl)ether, the (2-haloethyl)amines (nitrogen mustards), and sulfur sesquimustard, which has two α-chloroethyl thioether groups (ClH2CCH2S−) connected by an ethylene (−CH2CH2−) group. These compounds have a similar ability to alkylate DNA, but their physical properties, e.g. melting points, may vary.

Physiological effects

Soldier with moderate mustard agent burns sustained during World War I showing characteristic bullae on neck, armpit and hands

Mustard agent has extremely powerful vesicant effects on its victims. In addition, it is strongly mutagenic and carcinogenic, due to its alkylating properties. It is also lipophilic. Because people exposed to mustard agent rarely suffer immediate symptoms, and mustard-contaminated areas may appear completely normal, victims can unknowingly receive high dosages. Within 24 hours of exposure to mustard agent, victims experience intense itching and skin irritation, which gradually turns into large blisters filled with yellow fluid wherever the mustard agent contacted the skin. These are chemical burns and are very debilitating. Mustard agent vapor easily penetrates clothing fabrics such as wool or cotton, so it is not only the exposed skin of victims that gets burned. If the victim's eyes were exposed then they become sore, starting with conjunctivitis, after which the eyelids swell, resulting in temporary blindness. In rare cases of extreme ocular exposure to sulfur mustard vapors, corneal ulceration, anterior chamber scarring, and neovascularization have occurred. In these severe and infrequent cases, corneal transplantation has been used as a treatment option.[8] Miosis may also occur, which is probably the result from the cholinomimetic activity of mustard.[9] At very high concentrations, if inhaled, mustard agent causes bleeding and blistering within the respiratory system, damaging mucous membranes and causing pulmonary edema. Depending on the level of contamination, mustard agent burns can vary between first and second degree burns, though they can also be every bit as severe, disfiguring and dangerous as third degree burns.[10] Severe mustard agent burns (i.e. where more than 50% of the victim's skin has been burned) are often fatal, with death occurring after some weeks or even days have passed. Mild or moderate exposure to mustard agent is unlikely to kill, though victims require lengthy periods of medical treatment and convalescence before recovery is complete.

The mutagenic and carcinogenic effects of mustard agent mean that victims who recover from mustard agent burns have an increased risk of developing cancer in later life. In a study of patients 25 years after wartime exposure to chemical weaponry, c-DNA microarray profiling indicated that a total of specific 122 genes were significantly mutated in the lungs and airways of sulfur mustard victims. Those genes all correspond to functions commonly affected by sulfur mustard exposure, including apoptosis, inflammation, and stress responses.[11]

Typical appearance of bullae on arm caused by blister agent burns

The vesicant property of mustard agent can be neutralized by oxidation or chlorination, using household bleach (sodium hypochlorite), or by nucleophilic attack using e.g. decontamination solution "DS2" (2% NaOH, 70% diethylenetriamine, 28% ethylene glycol monomethyl ether). After initial decontamination of the victim's wounds is complete, medical treatment is similar to that required by any conventional burn. The amount of pain and discomfort suffered by the victim is comparable as well. Mustard agent burns heal slowly, and, as with other types of burn, there is a risk of sepsis caused by pathogens such as Staphylococcus aureus and Pseudomonas aeruginosa. The mechanisms behind sulfur mustard’s effect on endothelial cells are still being studied, but recent studies have shown that high levels of exposure can induce high rates of both necrosis and apoptosis. In vitro tests have shown that at low concentrations of sulfur mustard, where apoptosis is the predominant result of exposure, pretreatment with 50 mM N-acetyl-L-cystein (NAC) was able to decrease the rate of apoptosis. NAC protects actin filaments from reorganization by sulfur mustard, demonstrating that actin filaments play a large role in the severe burns observed in victims.[12]

A British nurse treating soldiers with mustard agent burns during World War I commented:[13]

They cannot be bandaged or touched. We cover them with a tent of propped-up sheets. Gas burns must be agonizing because usually the other cases do not complain, even with the worst wounds, but gas cases are invariably beyond endurance and they cannot help crying out.


In its history, various types and mixtures of sulfur mustard have been employed. These include:

Sulfur mustard agents (class)

The complete list of effective sulfur mustard agents commonly stockpiled is as follows:

Chemical Code Trivial name CAS number PubChem Structure
Bis(2-chloroethyl)sulfide H/HD Mustard 505-60-2 CID 10461 from PubChem
1,2-Bis-(2-chloroethylthio)-ethane Q Sesquimustard 3563-36-8 CID 19092 from PubChem
Bis-(2-chloroethylthioethyl)-ether T O-mustard 63918-89-8 CID 45452 from PubChem
2-Chloroethyl chloromethyl sulfide 2625-76-5
Bis-(2-chloroethylthio)-methane HK 63869-13-6
Bis-1,3-(2-chloroethylthio)-n-propane 63905-10-2
Bis-1,4-(2-chloroethylthio)-n-butane 142868-93-7
Bis-1,5-(2-chloroethylthio)-n-pentane 142868-94-8
Bis-(2-chloroethylthiomethyl)-ether 63918-90-1



Mustard agent was possibly developed as early as 1822 by César-Mansuète Despretz (1798–1863).[15] Despretz described the reaction of sulfur dichloride and ethylene but never made mention of any irritating properties of the reaction product, which makes the claim doubtful. In 1854, another French chemist, Alfred Riche (1829–1908), repeated this procedure but he did not describe any adverse physiological properties. In 1860, the British scientist Frederick Guthrie synthesized and characterized the mustard agent compound, and he also noted its irritating properties, especially in tasting.[16] In 1860, chemist Albert Niemann, known as a pioneer in cocaine chemistry, repeated the reaction, and recorded blister-forming properties. In 1886, Viktor Meyer published a paper describing a synthesis that produced good yields. He combined 2-chloroethanol with aqueous potassium sulfide, and then treated the resulting thiodiglycol with phosphorus trichloride. The purity of this compound was much higher, and the adverse health effects on exposure much more severe. These symptoms presented themselves in his assistant, and in order to rule out the possibility that his assistant was suffering from a mental illness (psychosomatic symptoms), Meyer had this compound tested on laboratory rabbits, most of which died. In 1913, the English chemist Hans Thacher Clarke (known for the Eschweiler-Clarke reaction) replaced the phosphorus trichloride with hydrochloric acid in Meyer's formulation while working with Emil Fischer in Berlin. Clarke was hospitalized for two months for burns after one of his flasks broke. According to Meyer, Fischer's report on this accident to the German Chemical Society sent the German Empire on the road to chemical weapons.[17]

Mustard agent can have the effect of turning a patient's skin different colors, including reds, oranges, pinks, and in unusual cases, blues. The German Empire during World War I relied on the Meyer-Clarke method as 2-chloroethanol was readily available from the German chemical dye industry of that time.


Pallets of 155 mm artillery shells containing "HD" (distilled sulfur mustard agent) at Pueblo chemical weapons storage facility. The distinctive color-coding scheme on each shell is visible

Mustard agent was first used effectively in World War I by the German army against British and Canadian soldiers near Ypres, Belgium, in 1917 and later also against the French Second Army. The name Yperite comes from its usage by the German army near the town of Ypres. The Allies did not use mustard agent until November 1917 at Cambrai, France, after the armies had captured a stockpile of German mustard-gas shells. It took the British more than a year to develop their own mustard agent weapon, with production of the chemicals centred on Avonmouth Docks.[18][19] (The only option available to the British was the Despretz–Niemann–Guthrie process). This was used first in September 1918 during the breaking of the Hindenburg Line.

Mustard agent was dispersed as an aerosol in a mixture with other chemicals, giving it a yellow-brown color and a distinctive odor. Mustard agent has also been dispersed in such munitions as aerial bombs, land mines, mortar rounds, artillery shells, and rockets.[1] Exposure to mustard agent was lethal in about one percent of cases. Its effectiveness was as an incapacitating agent. The early countermeasures against mustard agent were relatively ineffective, since a soldier wearing a gas mask was not protected against absorbing it through his skin and being blistered.

Mustard agent is a persistent weapon that remains on the ground for days and weeks, and it continues to cause ill effects. If mustard agent contaminates a soldier's clothing and equipment, then the other soldiers that he comes into contact with are also poisoned. Towards the end of World War I, mustard agent was used in high concentrations as an area-denial weapon that forced troops to abandon heavily-contaminated areas.

US Army World War II Gas Identification Poster, ca. 1941–1945

Since World War I, mustard agent has been used in several wars or other conflicts, usually against people who cannot retaliate in kind:[20]

In 1943, during the Second World War, an American shipment of mustard agent exploded aboard a supply ship that was bombed during an air raid in the harbor of Bari, Italy. Eighty-three of the 628 hospitalized victims who had been exposed to the mustard agent died.[28] The deaths and incident were partially classified for many years.

From 1943 to 1944, mustard agent experiments were performed on Australian service volunteers in tropical Queensland, Australia, by British Army and American experimenters, resulting in some severe injuries. One test site, the Brook Islands National Park, was chosen to simulate Pacific islands held by the Imperial Japanese Army.[29][30]

After WWII, stockpiled mustard agent was dumped by the British in the sea near Port Elizabeth, South Africa, resulting in burn cases among trawler crews.[31]

The use of poison gases, including mustard agent, during warfare is known as chemical warfare, and this kind of warfare was prohibited by the Geneva Protocol of 1925, and also by the later Chemical Weapons Convention of 1993. The latter agreement also prohibits the development, production, stockpiling, and sale of such weapons.

In September 2012 a US official stated that the rebel militant group ISIS was manufacturing and using sulfur mustard in Syria and Iraq, which was allegedly confirmed by their the group's head of chemical weapons development, Sleiman Daoud al-Afari, who has since been captured.[32][33][34]

Development of the first chemotherapy drug

As early as 1919 it was known that mustard agent was a suppressor of hematopoiesis.[35] In addition, autopsies performed on 75 soldiers who had died of mustard agent during World War I were done by researchers from the University of Pennsylvania who reported decreased counts of white blood cells.[28] This led the American Office of Scientific Research and Development (OSRD) to finance the biology and chemistry departments at Yale University to conduct research on the use of chemical warfare during World War II.[28][36] As a part of this effort, the group investigated nitrogen mustard as a therapy for Hodgkin's lymphoma and other types of lymphoma and leukemia, and this compound was tried out on its first human patient in December 1942. The results of this study were not published until 1946, when they were declassified.[36] In a parallel track, after the air raid on Bari in December 1943, the doctors of the U.S. Army noted that white blood cell counts were reduced in their patients. Some years after World War II was over, the incident in Bari and the work of the Yale University group with nitrogen mustard converged, and this prompted a search for other similar chemical compounds. Due to its use in previous studies, the nitrogen mustard called "HN2" became the first cancer chemotherapy drug, mustine, to be used.


Most of the sulfur mustard agent found in Nazi Germany after World War II was dumped into the Baltic Sea. Between 1966 and 2002, fishermen have found about 700 chemical weapons in the region of Bornholm, most of which contain sulfur mustard. One of the more frequently-dumped weapons was the "Sprühbüchse 37" (SprüBü37, Spray Can 37, 1937 being the year of its fielding with the German Army). These weapons contain sulfur mustard mixed with a thickener, which gives it a tar-like viscosity. When the content of the SprüBü37 comes in contact with water, only the sulfur mustard in the outer layers of the lumps of viscous mustard hydrolyzes, leaving behind amber-colored residues that still contain most of the active sulfur mustard. On mechanically breaking these lumps, e.g., with the drag board of a fishing net or by the human hand, the enclosed sulfur mustard is still as active as it had been at the time the weapon was dumped. These lumps, when washed ashore, can be mistaken for amber, which can lead to severe health problems. Artillery shells containing sulfur mustard and other toxic ammunition from World War I (as well as conventional explosives) can still be found in France and Belgium. These were formerly disposed of by explosion undersea, but since the current environmental regulations prohibit this, the French government is building an automated factory to dispose of the accumulation of chemical shells.

In 1972, the U.S. Congress banned the practice of disposing of chemical weapons into the ocean by the United States. 29000 tons of nerve and mustard agents had already been dumped into the ocean off the United States by the U.S. Army. According to a report created in 1998 by William Brankowitz, a deputy project manager in the U.S. Army Chemical Materials Agency, the army created at least 26 chemical weapons dumping sites in the ocean offshore from at least 11 states on both the East Coast and the West Coast (in Operation CHASE, Operation Geranium, etc.). In addition, due to poor recordkeeping, about one-half of the sites have only their rough locations known.[37]

A significant portion of the stockpile of mustard agent in the United States was stored at the Edgewood Area of Aberdeen Proving Ground in Maryland. Approximately 1,621 tons of mustard agent were stored in one-ton containers on the base under heavy guard. A chemical neutralization plant was built on the proving ground and neutralized the last of this stockpile in February 2005. This stockpile had priority because of the potential for quick reduction of risk to the community. The nearest schools were fitted with overpressurization machinery to protect the students and faculty in the event of a catastrophic explosion and fire at the site. These projects, as well as planning, equipment, and training assistance, were provided to the surrounding community as a part of the Chemical Stockpile Emergency Preparedness Program (CSEPP), a joint program of the Army and the Federal Emergency Management Agency (FEMA).[38] Unexploded shells containing mustard agent and other chemical agents are still present in several test ranges in proximity to schools in the Edgewood area, but the smaller amounts of poison gas (four to 14 pounds) present considerably lower risks. These remnants are being detected and excavated systematically for disposal. The U.S. Army Chemical Materials Agency oversaw disposal of several other chemical weapons stockpiles located across the United States in compliance with international chemical weapons treaties. These include the complete incineration of the chemical weapons stockpiled in Alabama, Arkansas, Indiana, and Oregon. Earlier, this agency had also completed destruction of the chemical weapons stockpile located on Johnston Atoll located south of Hawaii in the Pacific Ocean.[39] The largest mustard agent stockpile, of about 6,196 tons, was stored at the Deseret Chemical Depot in northern Utah. The incineration of this stockpile began in 2006. In May 2011, the last one-ton tank of mustard agent was incinerated at the Deseret Chemical Depot, and the last mustard agent artillery shells at Deseret were incinerated in January 2012.

In June 1997, India declared its stock of chemical weapons (1,044 tonnes of sulphur mustard).[40][41] By the end of 2006, India had destroyed more than 75 percent of its chemical weapons/material stockpile and was granted extension for destroying (the remaining stocks by April 2009) and was expected to achieve 100 percent destruction within that time frame.[40] India informed the United Nations in May 2009 that it had destroyed its stockpile of chemical weapons in compliance with the international Chemical Weapons Convention. With this India has become third country after South Korea and Albania to do so.[42][43] This was cross-checked by inspectors of the United Nations.

The storage and incineration of mustard agent and other poison gases was carried out by the U.S. Army Chemical Materials Agency.[44] Disposal projects at the two remaining American chemical weapons sites, will be carried out at their sites near Richmond, Kentucky, and Pueblo, Colorado.

In 2002, an archaeologist at the Presidio Trust archaeology lab in San Francisco was exposed to mustard agent, which had been dug up at the Presidio of San Francisco, a former military base.[45]

In 2008, many empty mustard agent aerial bombs were found in an excavation at the Marrangaroo Army Base just west of Sydney, Australia.[46][47] In 2009, a mining survey near Chinchilla, Queensland, uncovered 144 105-millimeter howitzer shells, some containing "Mustard H", that had been buried by the U.S. Army during World War II.[47][48]

In 2010, a clamming boat pulled up some old artillery shells of World War I from the Atlantic Ocean south of Long Island, New York. Multiple fishermen suffered from skin blistering and respiratory irritation severe enough to require their hospitalization.[49]

A large British stockpile of old mustard agent that had been made and stored at M. S. Factory, Valley near Rhydymwyn in Flintshire, Wales, since World War I was destroyed in 1958.[50]

In 2014, a collection of 200 bombs were found on the boundary between the Flemish villages of Passendale and Moorslede. The majority of the bombs were filled with mustard agent. The bombs are a leftover from the German army and were meant to be used in the Battle of Passchendale in World War I. It was the largest collection of chemical weapons ever found in Belgium.[51]

New detection techniques are being developed in order to detect the presence of sulfur mustard and its metabolites. The technology is portable and detects small quantities of the hazardous waste and its oxidized products, which are notorious for harming unsuspecting civilians. The immunochromatographic assay would eliminate the need for expensive, time-consuming lab tests and enable easy-to-read tests to protect civilians from sulfur-mustard dumping sites.[52]

Detection in biological fluids

Urinary concentrations of the thiodiglycol hydrolysis products of sulfur mustard have been used to confirm a diagnosis of chemical poisoning in hospitalized victims. The presence in urine of 1,1'-sulfonylbismethylthioethane (SBMTE), a conjugation product with glutathione, is considered a more specific marker, since this metabolite is not found in specimens from unexposed persons. Intact sulfur mustard was detected in postmortem fluids and tissues of a man who died one week post-exposure.[53]

See also


  1. 1 2 3 4 5 FM 3–8 Chemical Reference handbook, US Army, 1967
  2. See:
  3. Fischer, Karin (June 2004). Schattkowsky, Martina, ed. Steinkopf, Georg Wilhelm, in: Sächsische Biografie (in German) (Online ed.). Institut für Sächsische Geschichte und Volkskunde. Retrieved 2010-12-28.
  4. 1 2 Stewart, Charles D. (2006). Weapons of mass casualties and terrorism response handbook. Boston: Jones and Bartlett. p. 47. ISBN 0-7637-2425-4.
  5. 1 2 "Chemical Weapons Production and Storage". Federation of American Scientists. Archived from the original on August 11, 2014.
  6. Institute of Medicine (1993). Chapter 5: Chemistry of Sulfur Mustard and Lewisite. Veterans at Risk: The Health Effects of Mustard Gas and Lewisite. The National Academies Press. ISBN 0-309-04832-X.
  7. 1 2 3 Mustard agents: description, physical and chemical properties, mechanism of action, symptoms, antidotes and methods of treatment. Organisation for the Prohibition of Chemical Weapons. Accessed June 8, 2010.
  8. Safarinejad, M. R.; Moosavi, S. A.; Montazeri, B (2001). "Ocular injuries caused by mustard gas: diagnosis, treatment, and medical defense". Military Medicine. 166 (1): 67–70. PMID 11197102.
  9. Vesicants.
  10. Effects of mustard gas, WW1|Gas Warfare Medical Aspects|World War II Resource Centre. (2004-08-23). Retrieved on 2011-05-29.
  11. Najafi, Ali; Masoudi-Nejad, Ali; Imani Fooladi, Abbas Ali; Ghanei, Mostafa; Nourani, Mohamad Reza (2014). "Microarray gene expression analysis of the human airway in patients exposed to sulfur mustard". Journal of Receptors and Signal Transduction. 34 (4): 283. doi:10.3109/10799893.2014.896379. PMID 24823320.
  12. Dabrowska, Milena I.; Becks, Lauren L.; Lelli, Jr., Joseph L.; Levee, Minette G.; Hinshaw, Daniel B. (1996). "Sulfur Mustard Induces Apoptosis and Necrosis in Endothelial Cells". Toxicology and Applied Pharmacology. 141 (2): 568. doi:10.1006/taap.1996.0324. PMID 8975783.
  13. Van Bergen, Leo (2009). Before My Helpless Sight: Suffering, Dying and Military Medicine on the Western Front, 1914–1918. Ashgate Publishing, Ltd. p. 184. ISBN 978-0-7546-5853-5.
  14. The Emergency Response Safety and Health Database: Mustard-Lewisite Mixture (HL). National Institute for Occupational Safety and Health. Accessed March 19, 2009.
  15. By Any Other Name: Origins of Mustard Gas. (2008-04-25). Retrieved on 2011-05-29.
  16. F. Guthrie (1860). "XIII.—On some derivatives from the olefines". Q. J. Chem. Soc. 12 (1): 109–126. doi:10.1039/QJ8601200109.
  17. Duchovic, Ronald J.; Vilensky, Joel A. (2007). "Mustard Gas: Its Pre-World War I History". J. Chem. Educ. 84 (6): 944. doi:10.1021/ed084p944.
  18. Edited by David Large. The Port of Bristol, 1848-1884.
  19. "Photographic Archive of Avonmouth Bristol BS11". Retrieved 12 May 2014.
  20. 1 2 3 4 5 6 Blister Agent: Sulfur Mustard (H, HD, HS) Archived July 24, 2007, at the Wayback Machine.,
  21. 1 2 3 4 Pearson, Graham S. "Uses of CW since the First World War". Federation of American Scientitst. Archived from the original on August 22, 2010. Retrieved 2010-06-28.
  22. 1 2 Daniel Feakes (2003). "Global society and biological and chemical weapons". In Mary Kaldor, Helmut Anheier and Marlies Glasius. Global Civil Society Yearbook 2003 (PDF). Oxford University Press. pp. 87–117. ISBN 0-19-926655-7.
  23. Lyon, Alistair (2008-07-09). "Iran's Chemical Ali survivors still bear scars". Reuters. Retrieved 2008-11-17.
  24. Benschop, H. P.; van der Schans, G. P.; Noort, D.; Fidder, A.; Mars-Groenendijk, R. H.; de Jong, L. P. A. (1997). "Verification of Exposure to Sulfur Mustard in Two Casualties of the Iran-Iraq Conflict". Journal of Analytical Toxicology. 21 (4): 249–251. doi:10.1093/jat/21.4.249. ISSN 0146-4760. PMID 9248939.
  25. "More Than 600 Reported Chemical Exposure in Iraq, Pentagon Acknowledges". New York Times. 6 Nov 2014.
  26. "Veterans Hurt by Chemical Weapons in Iraq Get Apology". New York Times. 25 Mar 2015.
  27. Deutsch, Anthony (15 February 2016). "Samples confirm Islamic State used mustard gas in Iraq - diplomat". Reuters. Thomson Reuters. Retrieved 15 February 2016.
  28. 1 2 3 Faguet, Guy B. (2005). The War on Cancer. Springer. p. 71. ISBN 1-4020-3618-3.
  29. Goodwin, Bridget (1998). Keen as mustard: Britain's horrific chemical warfare experiments in Australia. University of Queensland Press, St. Lucia,. ISBN 978-0-7022-2941-1.
  30. Brook Island Trials of Mustard Gas during WW2. Retrieved on 2011-05-29.
  31. "NEWSLETTER - JUNE 1992 NEWSLETTER - Johannesburg - South African Military History Society - Title page". Retrieved 2013-08-23.
  32. Paul Blake (11 September 2015). "US official: 'IS making and using chemical weapons in Iraq and Syria'". BBC. Retrieved 16 September 2015.
  33. Lizzie Dearden (11 September 2015). "Isis 'manufacturing and using chemical weapons' in Iraq and Syria, US official claims". The Independent. Retrieved 16 September 2015.
  34. Jamie Schram (9 March 2016). "Captured ISIS head of chemical weapons says they've got mustard gas'". NYPost. Retrieved 9 March 2016.
  35. Krumbhaar EB (1919). "tole of the blood and the bone marrow in certain forms of gas poisoning". JAMA. 72: 39–41. doi:10.1001/jama.1919.26110010018009f.
  36. 1 2 Gilman A (May 1963). "The initial clinical trial of nitrogen mustard". Am. J. Surg. 105 (5): 574–8. doi:10.1016/0002-9610(63)90232-0. PMID 13947966.
  37. Bull, John (2005-10-30). "The Deadliness Below". Daily Press Virginia.
  38. "CSEPP Background Information". US Federal Emergency Management Agency (FEMA). 2 May 2006. Archived from the original on May 27, 2006.
  39. Milestones in U.S. Chemical Weapons Storage and Destruction, fact sheet, US Chemical Materials Agency
  40. 1 2 "India to destroy chemical weapons stockpile by 2009". Dominican Today. Archived from the original on September 7, 2013. Retrieved 30 April 2013.
  41. Smithson, Amy Gaffney, Frank, Jr.; 700+ words. "India declares its stock of chemical weapons". Retrieved 30 April 2013.
  42. "Zee News – India destroys its chemical weapons stockpile". 14 May 2009. Retrieved 30 April 2013.
  43. "Archived copy". Archived from the original on May 21, 2009. Retrieved May 20, 2009.
  44. The U.S. Army's Chemical Materials Agency (CMA). Retrieved on 2011-11-23.
  45. Sullivan, Kathleen (2002-10-22). "Vial found in Presidio may be mustard gas / Army experts expected to identify substance".
  46. Ashworth L (2008-08-07). "Base's phantom war reveals its secrets". Fairfax Digital. Archived from the original on December 5, 2008.
  47. 1 2 Chemical Warfare in Australia. Retrieved on 2011-05-29.
  48. Cumming, Stuart (2009-11-11). "Weapons await UN inspection". Toowoomba Chronicle.
  49. Wickett, Shana; Beth Daley (2010-06-08). "Fishing crewman exposed to mustard gas from shell". Boston Globe. Archived from the original on June 9, 2010.
  50. "Valley Factory, Rhydymwyn". 2010-07-24.
  51. "Farmer discovers 200 bombs (Dutch)". 2014-03-05.
  52. Sathe, Manisha; Srivastava, Shruti; Merwyn, S.; Agarwal, G. S.; Kaushik, M. P. (2014-07-24). "Competitive immunochromatographic assay for the detection of thiodiglycol sulfoxide, a degradation product of sulfur mustard (English)". The Analyst. 139 (20): 5118. doi:10.1039/C4AN00720D. PMID 25121638.
  53. R. Baselt, Disposition of Toxic Drugs and Chemicals in Man, 10th edition, Biomedical Publications, Seal Beach, CA, 2014, pp. 1892–1894.

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