Sigma-Aldrich Corporation
subsidiary of Merck KGaA
Traded as NASDAQ: SIAL
Industry chemicals
Founded August 1975
Headquarters St. Louis, Missouri
United States
Key people
Rakesh Sachdev, President and CEO[1]
Products life science technologies and specialty chemicals
Revenue US$ 2,785.0 million (2014)[2]
US$ 681.0 million (2014)[2]
US$ 500.0 million (2014)[2]
Total assets US$ 4,195.0 million (2014)[2]
Total equity US$ 3,130.0 million (2014)[2]
Number of employees
more than 9,600
Parent Merck KGaA (100%)[3]

Sigma-Aldrich Corporation is an American chemical, life science and biotechnology company owned by Merck KGaA.

Created by the 1975 merger of Sigma Chemical Company and Aldrich Chemical Company, Sigma-Aldrich since grew through various acquisitions until it had over 9,600 employees and was listed on the Fortune 1000 at the time of its acquisition by Merck. The company is headquartered in St. Louis and has operations in approximately 40 countries.[4]

In September 2014, the German company Merck KGaA announced that it would be acquiring Sigma-Aldrich for 17.0 billion dollars, pending approval from national regulatory agencies.[5] The acquisition was completed in November 2015 and Sigma-Aldrich became a subsidiary of Merck KGaA. The company is currently a part of Merck's life science business and in the USA and Canada operated as a part of MilliporeSigma.[6][7]


Sigma Chemical Company of St Louis and Aldrich Chemical Company of Milwaukee (founded by Alfred Bader) were both American specialty chemical companies when they merged in August 1975.[8] The company grew throughout the '80s and '90s, with significant expansion in facilities, acquisitions and diversification into new market sectors.

Other key events

Key numbers

Key numbers for Sigma-Aldrich.[2]




Geographies (% of 2008 sales):

Corporate structure

The company is divided into four business units, for which separate financial performance data are reported:[23]


The Aldrich Logo.

Aldrich is a supplier in the research and fine chemicals market. Aldrich provides organic and inorganic chemicals, building blocks, reagents, advanced materials and stable isotopes for chemical synthesis, medicinal chemistry and materials science. Aldrich's chemicals catalog, the "Aldrich Catalog and Handbook" is often used as a handbook due to the inclusion of structures, physical data, and literature references.

The Sigma Logo.

Sigma is the Sigma-Aldrich's main biochemical supplier, with offerings including antibiotics, buffers, carbohydrates, enzymes, forensic tools, hematology and histology, nucleotides, proteins, peptides, amino acids and their derivatives.

The Sigma RBI Logo.

Sigma RBI produces specialized products for use in the field of cell signaling and neuroscience. Their offerings range from standard biochemical reagents to specialized research tools, including ligands for receptors and ion channels, enzyme inhibitors, phosphospecific antibodies, key signal transduction enzymes, and assay kits for cell signaling.

The ISOTEC Logo.

ISOTEC provides isotopically labeled products for protein structure determination, peptide synthesis, proteomics, metabolic research, magnetic resonance imaging, nuclear magnetic resonance, breath test substrates, agriculture, as well as gas and gas mixes.

The Fluka Logo.

Fluka manufactures chemicals and reagents for analytical, organic and biochemical research, and intermediates for the chemical and pharmaceutical industries.

The Riedel-de Haën Logo.

Riedel-de Haën was incorporated with Sigma-Aldrich in 1999 and manufactures reagents and standards.

The Supelco Logo.

Supelco is the chromatography products branch of Sigma-Aldrich. It provides chromatography columns and related tools for environmental, government, food and beverage, pharmaceutical, biotechnology, medical and chemical laboratories; sample preparation products and chemical reference standards.

The SAFC Logo.

Sigma-Aldrich Fine Chemicals (SAFC) is the fine chemical supply branch of Sigma-Aldrich specializing in raw materials for cell culture products; customized services for raw materials, manufacturing of active pharmaceutical ingredients.

Sigma Life Science provides products such as custom DNA/RNA oligos; custom DNA and LNA probes; siRNA; isotopically-labelled peptides and peptide libraries.

Sigma Advanced Genetic Engineering (SAGE) Labs is a division within Sigma-Aldrich that specializes in genetic manipulation of in vivo systems for special research and development applications. It was formed in 2008 to investigate zinc finger nuclease technology and its application for disease research models. Located in St. Louis, Missouri, SAGE Labs have developed knockout rats for the study of human diseases and disorders (such as autism), which are sold for up to US$95,000. SAGE also announced its first successful effort in creating a "knockout rabbit".[24] Its facilities include a specific pathogen free, biosecure vivarium as well as research and development labs.

Carbolabs produces research quantities of chemicals produced by phosgenation reactions. The company was acquired in 1998.[25]

BioReliance provides testing and manufacturing services to pharmaceutical and biopharmaceutical companies that span the product cycle from early pre-clinical development to licensed production. The company was acquired by Sigma Aldrich in January 2012.


Sigma-Aldrich is located in 40 countries world-wide. In territories where they are not present, Sigma-Aldrich operates through a network of authorized distributors. A list of them can be found below:

The company also operates an eCommerce platform "which offers 24-hour delivery in major markets."[20]


Sigma-Aldrich has been recognized for its commitment to the community and environment numerous times:


  1. Sigma-Aldrich - Board of Directors
  2. 1 2 3 4 5 6 "SIGMA ALDRICH CORP (10-K), Consolidated Statements of Income" (XBRL). United States Securities and Exchange Commission. February 12, 2015.
  3. "Defunct" (XBRL). Merck. November 18, 2015.
  4. "Sigma-Aldrich Corporation – Investor Relations".
  5. ""Sigma-Aldrich, Merck KGaA Press Release, 22 Sept. 2014" (PDF).
  6. Customer Letter
  7. About Us, EMD Millipore + Sigma-Aldrich = MilliporeSigma, The life science business of Merck KGaA, Darmstadt, Germany
  8. "Funding Universe History of Sigma-Aldrich Corporation". Funding-Universe.
  9. "Sigma-Aldrich Corp acquires Isotec Inc from Taiyo Nippon Sanso Corp".
  10. "Sigma-Aldrich Corp acquires Ultrafine".
  11. "Sigma-Aldrich Corp acquires JRH Biosciences Inc from CSL Ltd".
  12. "NCBI on Sigma-Aldrich".
  13. "Sigma-Aldrich Corp acquires Beijing Superior Chem & Instr".
  14. "Sigma-Aldrich Corp acquires Pharmorphix Ltd".
  15. "Sigma-Aldrich Corp acquires Advanced Separation Tech Inc from Calgon Carbon Corp".
  16. "Sigma-Aldrich Corp acquires Epichem Group Ltd".
  17. Associated Press (9 Jan 2012), "Sigma-Aldrich to buy BioReliance Hldgs for $350M", News, Bioscience Technology, retrieved 11 Jan 2012
  18. Invitrogen Completes Divestiture of BioReliance (press release), Life Technologies, 12 April 2007, retrieved 11 Jan 2012
  19. Ludwig Burger (September 22, 2014). "Germany's Merck to buy Sigma-Aldrich for $17 billion to boost lab supplies operation". Reuters. Retrieved September 23, 2014.
  20. 1 2 Staff (October 15, 2014). "Merck KGaA to Acquire Sigma-Aldrich for $17B". Genetic Engineering & Biotechnology News. p. 10.
  21. "Sigma-Aldrich Corporation Announces Filing Of Definitive Proxy Statement And Date Of Special Meeting Of Stockholders". Acquire Media. Retrieved 3 November 2014. External link in |website= (help)
  22. "Sigma-Aldrich Corporate Fact Sheet" (PDF).
  23. "Sigma-Aldrich Corporation Quarterly Report, May 2009".
  24. "SAGE's Latest Knockout: $95,000 Lab Rats". Fast Company.
  25. "Carbolabs purchased". ICIS.
  26. "Distributor Nigeria".
  27. "Distributor Turkey".
  28. "Distributor Romania".
  29. "2015 Global 100". Corporate Knights.
  30. "Dow Jones Sustainability North America Index" (PDF).
  31. "Carbon Disclosure Leadership Index" (PDF).
  32. "Corporate Responsibility Magazine, 100 Best Corp Citizens List 2014" (PDF).
  33. "Civic50".
  34. "Maplecroft Climate Innovation Indexes".
  35. "Trucost Natural Capital Leaders, by Industry, 2014" (PDF).

Media related to Sigma-Aldrich at Wikimedia Commons

This article is issued from Wikipedia - version of the 10/19/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.