ScaRNAs
| Small Cajal body RNA | |
|---|---|
|
Predicted secondary structure of Small Cajal body RNA | |
| Identifiers | |
| Symbol | SCARNA1 |
| Rfam | RF00553 |
| Other data | |
| RNA type | gene, snRNA, snoRNA, scaRNAs; |
| Domain(s) | Vertebrata |
| SO | {{{SO}}} |
The scaRNAs[1] (Small Cajal body RNA genes) resemble snoRNAs and perform a similar role in RNA maturation, but their targets are spliceosomal snRNAs and they perform site-specific modifications of spliceosomal snRNA precursors in the Cajal bodies of the nucleus. There are at least 25 human genes, each specifying one type of scaRNA. Like snoRNA genes, the scaRNA genes are typically located within the introns of genes transcribed by RNA polymerase II[2]
References
- ↑ Deryusheva, S.; Gall, J. G. (22 October 2013). "Novel small Cajal-body-specific RNAs identified in Drosophila: probing guide RNA function". RNA. 19 (12): 1802–1814. doi:10.1261/rna.042028.113.
- ↑ Strachan, Tom; Read, Andrew (2011). Human molecular genetics (4th ed.). New York: Garland Science. ISBN 978-0-815-34149-9.
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