SKF-38,393
 | |
| Identifiers | |
|---|---|
| |
| CAS Number | 67287-49-4 |
| PubChem (CID) | 1242 |
| IUPHAR/BPS | 935 |
| ChemSpider | 1205 |
| ChEBI |
CHEBI:131793  Y |
| ChEMBL |
CHEMBL24077 Y |
| Chemical and physical data | |
| Formula | C16H17NO2 |
| Molar mass | 255.31 g/mol |
| 3D model (Jmol) | Interactive image |
| |
SKF-38,393 is a synthetic compound of the benzazepine chemical class which acts as a selective D1/D5 receptor partial agonist.[1] It has stimulant and anorectic effects.[2][3]
References
- ↑ Dubois A, Savasta M, Curet O, Scatton B (September 1986). "Autoradiographic distribution of the D1 agonist [3H]SKF 38393, in the rat brain and spinal cord. Comparison with the distribution of D2 dopamine receptors". Neuroscience. 19 (1): 125–37. doi:10.1016/0306-4522(86)90010-2. PMID 2946980.
- ↑ Trampus M, Ferri N, Adami M, Ongini E (April 1993). "The dopamine D1 receptor agonists, A68930 and SKF 38393, induce arousal and suppress REM sleep in the rat". European Journal of Pharmacology. 235 (1): 83–7. doi:10.1016/0014-2999(93)90823-Z. PMID 8100197.
- ↑ Cooper SJ, Francis J, Rusk IN (1990). "The anorectic effect of SK&F 38393, a selective dopamine D1 receptor agonist: a microstructural analysis of feeding and related behaviour". Psychopharmacology. 100 (2): 182–7. doi:10.1007/BF02244403. PMID 1968277.
| D1-like |
| ||||||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D2-like |
| ||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
This article is issued from Wikipedia - version of the 6/3/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.