CAS Number 67287-49-4
PubChem (CID) 1242
ChemSpider 1205
ChEBI CHEBI:131793 YesY
Chemical and physical data
Formula C16H17NO2
Molar mass 255.31 g/mol
3D model (Jmol) Interactive image

SKF-38,393 is a synthetic compound of the benzazepine chemical class which acts as a selective D1/D5 receptor partial agonist.[1] It has stimulant and anorectic effects.[2][3]


  1. Dubois A, Savasta M, Curet O, Scatton B (September 1986). "Autoradiographic distribution of the D1 agonist [3H]SKF 38393, in the rat brain and spinal cord. Comparison with the distribution of D2 dopamine receptors". Neuroscience. 19 (1): 125–37. doi:10.1016/0306-4522(86)90010-2. PMID 2946980.
  2. Trampus M, Ferri N, Adami M, Ongini E (April 1993). "The dopamine D1 receptor agonists, A68930 and SKF 38393, induce arousal and suppress REM sleep in the rat". European Journal of Pharmacology. 235 (1): 83–7. doi:10.1016/0014-2999(93)90823-Z. PMID 8100197.
  3. Cooper SJ, Francis J, Rusk IN (1990). "The anorectic effect of SK&F 38393, a selective dopamine D1 receptor agonist: a microstructural analysis of feeding and related behaviour". Psychopharmacology. 100 (2): 182–7. doi:10.1007/BF02244403. PMID 1968277.

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