Reynolds' pentad

Reynolds pentad is a collection of signs and symptoms suggesting the diagnosis obstructive ascending cholangitis, a serious infection of the biliary system. It is a combination of Charcot's triad (jaundice, fever, abdominal pain (usually RUQ)) with shock and an altered mental status.[1] Or sometimes the two additional signs are listed simply as low blood pressure and confusion.[2]


It was named after the surgeon, B.M. Reynolds, who described it in 1959 along with Dr. Everett L. Dargan.[1]


  1. 1 2 Reynolds BM, Dargan EL (August 1959). "Acute obstructive cholangitis; a distinct clinical syndrome". Ann Surg. 150 (2): 299–303. doi:10.1097/00000658-195908000-00013. PMC 1613362Freely accessible. PMID 13670595.
  2. Sam, Amir H.; James T.H. Teo (2010). Rapid Medicine. Wiley-Blackwell. ISBN 1405183233.

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