RYBP

RYBP
Available structures
PDBHuman UniProt search: PDBe RCSB
Identifiers
Aliases RYBP, AAP1, DEDAF, YEAF1, APAP-1, RING1 and YY1 binding protein
External IDs MGI: 3648043 HomoloGene: 8159 GeneCards: RYBP
RNA expression pattern




More reference expression data
Orthologs
Species Human Mouse
Entrez

23429

628746

Ensembl

n/a

n/a

UniProt

Q8N488

n/a

RefSeq (mRNA)

NM_012234

n/a

RefSeq (protein)

NP_036366.3

n/a

Location (UCSC) Chr 3: 72.37 – 72.45 Mb n/a
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

RING1 and YY1-binding protein is a protein that in humans is encoded by the RYBP gene.[3][4]

Interactions

RYBP has been shown to interact with:

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. 1 2 3 4 García E, Marcos-Gutiérrez C, del Mar Lorente M, Moreno JC, Vidal M (Jun 1999). "RYBP, a new repressor protein that interacts with components of the mammalian Polycomb complex, and with the transcription factor YY1". The EMBO Journal. 18 (12): 3404–18. doi:10.1093/emboj/18.12.3404. PMC 1171420Freely accessible. PMID 10369680.
  4. "Entrez Gene: RYBP RING1 and YY1 binding protein".
  5. Zhu J, Shore SK (Dec 1996). "c-ABL tyrosine kinase activity is regulated by association with a novel SH3-domain-binding protein". Molecular and Cellular Biology. 16 (12): 7054–62. doi:10.1128/mcb.16.12.7054. PMC 231708Freely accessible. PMID 8943360.
  6. Zheng L, Schickling O, Peter ME, Lenardo MJ (Aug 2001). "The death effector domain-associated factor plays distinct regulatory roles in the nucleus and cytoplasm". The Journal of Biological Chemistry. 276 (34): 31945–52. doi:10.1074/jbc.M102799200. PMID 11395500.
  7. 1 2 Schlisio S, Halperin T, Vidal M, Nevins JR (Nov 2002). "Interaction of YY1 with E2Fs, mediated by RYBP, provides a mechanism for specificity of E2F function". The EMBO Journal. 21 (21): 5775–86. doi:10.1093/emboj/cdf577. PMC 131074Freely accessible. PMID 12411495.
  8. Chen D, Zhang J, Li M, Rayburn ER, Wang H, Zhang R (Feb 2009). "RYBP stabilizes p53 by modulating MDM2". EMBO Reports. 10 (2): 166–72. doi:10.1038/embor.2008.231. PMC 2637313Freely accessible. PMID 19098711.
  9. Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.

Further reading

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