ZNF364

RNF115

Identifiers

RNF115, BCA2, ZNF364, ring finger protein 115

External IDs

MGI: 1915095 HomoloGene: 69167 GeneCards: RNF115

Gene ontology
Molecular function	• zinc ion binding • ligase activity • protein binding • metal ion binding • ubiquitin protein ligase activity • ubiquitin-protein transferase activity
Cellular component	• cytoplasm • cytosol
Biological process	• protein K63-linked ubiquitination • protein ubiquitination involved in ubiquitin-dependent protein catabolic process • protein K48-linked ubiquitination • ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway • negative regulation of epidermal growth factor receptor signaling pathway • protein ubiquitination • proteasome-mediated ubiquitin-dependent protein catabolic process • protein autoubiquitination • protein polyubiquitination
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse


27246


67845


ENSG00000265491


ENSMUSG00000028098


Q9Y4L5


Q9D0C1

RefSeq (mRNA)


NM_014455


NM_026406

RefSeq (protein)


NP_055270.1


NP_080682.3

Location (UCSC)

Chr 1: 145.74 – 145.82 Mb

Chr 3: 96.73 – 96.79 Mb

PubMed search

^[1]

^[2]

View/Edit Human

View/Edit Mouse

RING finger protein 115 is a protein that in humans is encoded by the RNF115 gene.^[3]

References

Further reading

Burger A, Amemiya Y, Kitching R, Seth AK (2006). "Novel RING E3 ubiquitin ligases in breast cancer.". Neoplasia. 8 (8): 689–95. doi:10.1593/neo.06469. PMC 1601945. PMID 16925951.
Sakane A, Hatakeyama S, Sasaki T (2007). "Involvement of Rabring7 in EGF receptor degradation as an E3 ligase.". Biochem. Biophys. Res. Commun. 357 (4): 1058–64. doi:10.1016/j.bbrc.2007.04.052. PMID 17462600.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature. 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.
Burger AM, Gao Y, Amemiya Y, et al. (2006). "A novel RING-type ubiquitin ligase breast cancer-associated gene 2 correlates with outcome in invasive breast cancer.". Cancer Res. 65 (22): 10401–12. doi:10.1158/0008-5472.CAN-05-2103. PMID 16288031.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Mizuno K, Kitamura A, Sasaki T (2004). "Rabring7, a novel Rab7 target protein with a RING finger motif.". Mol. Biol. Cell. 14 (9): 3741–52. doi:10.1091/mbc.E02-08-0495. PMC 196564. PMID 12972561.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Suzuki H, Fukunishi Y, Kagawa I, et al. (2001). "Protein-protein interaction panel using mouse full-length cDNAs.". Genome Res. 11 (10): 1758–65. doi:10.1101/gr.180101. PMC 311163. PMID 11591653.

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