Pyrazolylalanine synthase
| pyrazolylalanine synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 4.2.1.50 | ||||||||
| CAS number | 37290-81-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / EGO | ||||||||
| |||||||||
In enzymology, a pyrazolylalanine synthase (EC 4.2.1.50) is an enzyme that catalyzes the chemical reaction
- L-serine + pyrazole 3-(pyrazol-1-yl)-L-alanine + H2O
Thus, the two substrates of this enzyme are L-serine and pyrazole, whereas its two products are 3-(pyrazol-1-yl)-L-alanine and H2O.
This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is L-serine hydro-lyase [adding pyrazole 3-(pyrazol-1-yl)-L-alanine-forming]. Other names in common use include beta-pyrazolylalaninase, beta-(1-pyrazolyl)alanine synthase, and L-serine hydro-lyase (adding pyrazole). It employs one cofactor, pyridoxal phosphate.
References
- Dunnill PM; Fowden L (1963). "The biosynthesis of beta-pyrazol-1-ylalanine". J. Exp. Bot. 14: 237–248. doi:10.1093/jxb/14.2.237.
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