Prostaglandin E

PGE1 - Alprostadil
PGE2 - Dinoprostone

Prostaglandin E is a family of naturally occurring prostaglandins and may be used pharmaceutically in medicine.

Types include:

It is created from prostaglandin E synthase.

It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.[1]

Prostaglandin E2

Prostaglandin E2 is secreted in microvessels by the endothelium. It is a direct vasodilator and it inhibits the release of noradrenaline from sympathetic nerve terminals. It doesn't have the effect on platelets PGI2 does.


  1. "WHO Model List of EssentialMedicines" (PDF). World Health Organization. October 2013. Retrieved 22 April 2014.

Pharmacology 2007. Rang, Dale, Ritter, Flower. Churchill Livingstone Elsevier.

External links

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