Prion pseudoknot

Prion pseudoknot
Predicted secondary structure and sequence conservation of Prion_pknot
Identifiers
Symbol Prion_pknot
Rfam RF00523
Other data
RNA type Cis-reg
Domain(s) Eukaryota
SO 0000233

The prion pseudoknot is predicted RNA pseudoknot structure found in prion protein mRNA.[1] It has been suggested that this element has a possible effect in prion protein translation.[2] The human prion protein contains 5 copies of a 24 nucleotide repeat that contains this structure.[2]

References

  1. Wills, PR (Dec 21, 1992). "Potential pseudoknots in the PrP-encoding mRNA.". Journal of Theoretical Biology. 159 (4): 523–7. doi:10.1016/S0022-5193(05)80696-4. PMID 1296103.
  2. 1 2 Barrette, I; Poisson G; Gendron P; Major F (2001). "Pseudoknots in prion protein mRNAs confirmed by comparative sequence analysis and pattern searching". Nucleic Acids Res. 29 (3): 753758. doi:10.1093/nar/29.3.753. PMC 30388Freely accessible. PMID 11160898.

External links


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