Pogosta disease
| Pogosta disease Karelian fever Ockelbo disease | |
|---|---|
| Classification and external resources | |
| ICD-10 | A92.8[1] |
Pogosta disease is a viral disease, established to be identical with other diseases, Karelian fever and Ockelbo disease.[2][3] The names are derived from the words Pogosta, Karelia and Ockelbo, respectively.
The symptoms of the disease include usually rash, as well as mild fever and other flu-like symptoms; in most cases the symptoms last less than 5 days. However, in some cases, the patients develop a painful arthritis. There are no known chemical agents available to treat the disease.[4]
It has long been suspected that the disease is caused by a Sindbis-like virus, a positive-stranded RNA virus belonging to the Alphavirus genus and family Togaviridae.[2] In 2002 a strain of Sindbis was isolated from patients during an outbreak of the Pogosta disease in Finland, confirming the hypothesis.[4]
This disease is mainly found in the Eastern parts of Finland; a typical Pogosta disease patient is a middle-aged person who has been infected through a mosquito bite while picking berries in the autumn. The prevalence of the disease is about 100 diagnosed cases every year, with larger outbreaks occurring in 7-year intervals.[4]
References
- ↑ "Internetmedicin: Ockelbosjukan". Retrieved March 19, 2015.
- 1 2 Lvov, D. K.; Vladimirtseva, E. A.; Butenko, A. M.; Karabatsos, N.; Trent, D. W.; Calisher, C. H. (1988). "Identity of Karelian fever and Ockelbo viruses determined by serum dilution-plaque reduction neutralization tests and oligonucleotide mapping". The American journal of tropical medicine and hygiene. 39 (6): 607–610. PMID 2849885.
- ↑ Laine, Maria (2002). Pogosta Disease. University of Turku. ISBN 951-29-2129-4.
- 1 2 3 Kurkela S, Manni T, Vaheri A, Vapalahti O (May 2004). "Causative agent of Pogosta disease isolated from blood and skin lesions". Emerg Infect Dis. 10 (5). doi:10.3201/eid1005.030689.