7 February 1931|
|Institutions||Institute for Genetics and Cellular and Molecular Biology|
|Known for||nuclear hormone receptors|
Richard Lounsbery Award (1982)|
Harvey Prize (1987)
Louisa Gross Horwitz Prize
Albert Lasker Award for Basic Medical Research
Alfred P. Sloan, Jr. Prize (2003)
Gairdner Foundation International Award (2010)
Pierre Chambon (born 7 February 1931, Mulhouse, France) was the founder of the Institute for Genetics and Cellular and Molecular Biology in Strasbourg, France. He was one of the leading molecular biologists who utilized gene cloning and sequencing technology to first decipher the structure of eukaryotic genes and their modes of regulation. His major contributions to science include the identification of RNA polymerase II(B), the identification of transcriptional control elements, the cloning and dissection of nuclear hormone receptors, revealing their structure and showing how they contribute to human physiology. He accomplished much of his work in the 1970-90s.
Chambon was elected a Foreign Associate of the US National Academy of Sciences and to the French Academie des Sciences in 1985, a foreign member of the Royal Swedish Academy of Sciences in 1987. He was awarded the Louisa Gross Horwitz Prize from Columbia University in 1999. In 2003 he was awarded the March of Dimes Prize in Developmental Biology. He received the Albert Lasker Award for Basic Medical Research in 2004 for his work in the field. In 2010, Chambon was awarded the Gairdner Foundation International Award "for the elucidation of fundamental mechanisms of transcription in animal cells and to the discovery of the nuclear receptor superfamily".