Pholedrine (Paredrinol, Pulsotyl, Veritol), also known as 4-hydroxy-N-methylamphetamine (4-HMA), 4-hydroxymethamphetamine, and para-hydroxymethamphetamine, is a drug that stimulates the sympathetic nervous system. It is administered as a topical eye drop form for the purpose of dilating the pupil and can be used to diagnose Horner's syndrome.
Metabolic pathways of methamphetamine
Pholedrine is one of methamphetamine
's two immediate metabolites in humans.
- ↑ P-HYDROXYMETHAMPHETAMINE CAS#: 370-14-9
- 1 2 Bates, A. T.; Chamberlain, S.; Champion, M.; Foley, L.; Hughes, E.; Jani, B.; Mehta, H.; Smith, S. E. (1995). "Pholedrine: A substitute for hydroxyamphetamine as a diagnostic eyedrop test in Horner's syndrome". Journal of neurology, neurosurgery, and psychiatry. 58 (2): 215–217. doi:10.1136/jnnp.58.2.215. PMC 1073320. PMID 7876854.