POLR1C

POLR1C
Identifiers
Aliases POLR1C, RPA39, RPA40, RPA5, RPAC1, TCS3, AC40, RPC40, HLD11, polymerase (RNA) I subunit C
External IDs MGI: 103288 HomoloGene: 3586 GeneCards: POLR1C
RNA expression pattern


More reference expression data
Orthologs
Species Human Mouse
Entrez

9533

20016

Ensembl

ENSG00000171453

ENSMUSG00000067148

UniProt

O15160

P52432

RefSeq (mRNA)

NM_004875
NM_203290
NM_001318876

NM_009085

RefSeq (protein)

NP_976035.1
NP_001305805.1

NP_033111.2

Location (UCSC) Chr 6: 43.51 – 43.53 Mb Chr 17: 46.24 – 46.25 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

DNA-directed RNA polymerases I and III subunit RPAC1 is a protein that in humans is encoded by the POLR1C gene.[3][4][5]

Interactions

POLR1C has been shown to interact with CD3EAP,[6] POLR1E[6][7][8] and POLR1D.[9][10]

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Zhang QH, Ye M, Wu XY, Ren SX, Zhao M, Zhao CJ, Fu G, Shen Y, Fan HY, Lu G, Zhong M, Xu XR, Han ZG, Zhang JW, Tao J, Huang QH, Zhou J, Hu GX, Gu J, Chen SJ, Chen Z (Oct 2000). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Research. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934Freely accessible. PMID 11042152.
  4. Dundr M, Hoffmann-Rohrer U, Hu Q, Grummt I, Rothblum LI, Phair RD, Misteli T (Nov 2002). "A kinetic framework for a mammalian RNA polymerase in vivo". Science. 298 (5598): 1623–6. doi:10.1126/science.1076164. PMID 12446911.
  5. "Entrez Gene: POLR1C polymerase (RNA) I polypeptide C, 30kDa".
  6. 1 2 Yamamoto K, Yamamoto M, Hanada K, Nogi Y, Matsuyama T, Muramatsu M (Jul 2004). "Multiple protein-protein interactions by RNA polymerase I-associated factor PAF49 and role of PAF49 in rRNA transcription". Molecular and Cellular Biology. 24 (14): 6338–49. doi:10.1128/MCB.24.14.6338-6349.2004. PMC 434256Freely accessible. PMID 15226435.
  7. Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Molecular Systems Biology. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948Freely accessible. PMID 17353931.
  8. Seither P, Zatsepina O, Hoffmann M, Grummt I (Sep 1997). "Constitutive and strong association of PAF53 with RNA polymerase I". Chromosoma. 106 (4): 216–25. doi:10.1007/s004120050242. PMID 9254723.
  9. Yao Y, Yamamoto K, Nishi Y, Nogi Y, Muramatsu M (Dec 1996). "Mouse RNA polymerase I 16-kDa subunit able to associate with 40-kDa subunit is a homolog of yeast AC19 subunit of RNA polymerases I and III". The Journal of Biological Chemistry. 271 (51): 32881–5. doi:10.1074/jbc.271.51.32881. PMID 8955128.
  10. Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.

Further reading


This article is issued from Wikipedia - version of the 7/2/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.