PIGW

PIGW
Identifiers
Aliases PIGW, Gwt1, HPMRS5, phosphatidylinositol glycan anchor biosynthesis class W
External IDs MGI: 1917575 HomoloGene: 6243 GeneCards: PIGW
Orthologs
Species Human Mouse
Entrez

284098

70325

Ensembl

n/a

ENSMUSG00000045140

UniProt

Q7Z7B1

Q8C398

RefSeq (mRNA)

NM_178517

NM_001077636
NM_027388

RefSeq (protein)

NP_848612.2

NP_001071104.1
NP_081664.2

Location (UCSC) Chr 17: 36.54 – 36.54 Mb Chr 11: 84.88 – 84.88 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Phosphatidylinositol glycan anchor biosynthesis class W is a protein that in humans is encoded by the PIGW gene. [3]

Function

Glycosylphosphatidylinositol (GPI) is a complex glycolipid that anchors many proteins to the cell surface. PIGW acts in the third step of GPI biosynthesis and acylates the inositol ring of phosphatidylinositol (Murakami et al., 2003 [PubMed 14517336]).

References

  1. ↑ "Human PubMed Reference:".
  2. ↑ "Mouse PubMed Reference:".
  3. ↑ "Entrez Gene: Phosphatidylinositol glycan anchor biosynthesis class W". Retrieved 2016-10-29.

Further reading


This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article is issued from Wikipedia - version of the 10/29/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.