Clinical data
ATC code none
Legal status
Legal status
  • Uncontrolled
CAS Number 365-26-4 N
PubChem (CID) 9701
ChemSpider 9320 YesY
KEGG D08314 YesY
ECHA InfoCard 100.006.067
Chemical and physical data
Formula C10H15NO2
Molar mass 181.23 g/mol
 NYesY (what is this?)  (verify)

Oxilofrine (also known as methylsynephrine, hydroxyephrine, oxyephrine, and 4-HMP) is a stimulant drug[1] and is an amphetamine chemically related to ephedrine and to synephrine.

Oxilofrine is currently a WADA prohibited substance when used in competition.[2] It is an ingredient found in some dietary supplements.

Publicized cases


  1. Fourcroy, Jean L. (2008). Pharmacology, doping and sports: a scientific guide for athletes, coaches, physicians, scientists and administrators. Taylor & Francis. ISBN 978-0-415-42845-3.
  2. http://list.wada-ama.org/prohibited-in-competition/prohibited-substances/
  3. Charles Pelkey (2010-04-13). "Oliveira suspended for two years". Velonews.
  4. Charles Pelkey (2011-02-24). "Court of Arbitration for Sport reduces Flavia Oliveira suspension". Velonews.
  5. Reuters. "Jamaicans Powell, Simpson test positive - SuperSport - Athletics". SuperSport. Retrieved 2013-07-15.
  6. "Jamaican Sprinter Asafa Powell slapped 18-month ban for doping". IANS. news.biharprabha.com. Retrieved 10 April 2014.
  7. "Asafa Powell banned for 18 months for doping". BBC Sport. 10 April 2014. Archived from the original on 9 May 2014.
  8. Drayton, John (14 July 2014). "Asafa Powell and Sherone Simpson given green light to return to action after sprinters have doping bans reduced to six months". Mail Online. Retrieved 14 July 2014.
  9. Danny Wild (16 July 2015). "Red Sox No. 10 prospect Kopech suspended". MiLB.com. Retrieved 8 March 2016.

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