Clinical data
ATC code none
Legal status
Legal status
  • Uncontrolled
Pharmacokinetic data
Biological half-life 4–16 days
CAS Number 126924-38-7
PubChem (CID) 4541
DrugBank DB06731
ChemSpider 4382
UNII 25CO3X0R31 YesY
Chemical and physical data
Formula C16H16F3NO
Molar mass 295.30 g/mol

Seproxetine, also known as (S)-norfluoxetine, is a selective serotonin reuptake inhibitor (SSRI).[1] It is the most important active metabolite of the widely used antidepressant fluoxetine, but little is known about its pharmacological actions. Seproxetine was being investigated by Eli Lilly and Company as an antidepressant; however, a cardiac side effect was noted and development was discontinued.


  1. "Seproxetine". DrugBank. University of Alberta. Retrieved 10 August 2016.
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