| IUPAC name
|3D model (Jmol)|| Interactive image|
|Molar mass||89.05 g·mol−1|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
- Arabinopyranosyl-N-methyl-N-nitrosourea (Aranose)
- Carmustine (BCNU, BiCNU)
- Ethylnitrosourea (ENU)
- Lomustine (CCNU)
- N-Nitroso-N-methylurea (NMU)
- Ranimustine (MCNU)
- Streptozocin (Streptozotocin)
Nitrosourea compounds are DNA alkylating agents and are often used in chemotherapy. They are lipophilic and thus can cross the blood–brain barrier, making them useful in the treatment of brain tumors such as glioblastoma multiforme.
Some nitrosoureas (e.g. lomustine) have been associated with the development of interstitial lung disease.
- "Antineop". Retrieved 2009-01-24.
- Takimoto CH, Calvo E. "Principles of oncologic pharmacotherapy". in Pazdur R, Wagman LD, Camphausen KA, Hoskins WJ (Eds) Cancer management: a multidisciplinary approach. 11 ed. 2008.
- Tucci E, Verdiani P, Di Carlo S, Sforza V (1986). "Lomustine (CCNU)-induced pulmonary fibrosis". Tumori. 72 (1): 95–8. PMID 3952821.
- Nitrosourea Compounds at the US National Library of Medicine Medical Subject Headings (MeSH)
- DDB 9052