Legal status
Legal status
CAS Number 837122-21-7
PubChem (CID) 91864534
ChemSpider 30922478
Chemical and physical data
Formula C24H22FNO2
Molar mass 375.4 g/mol
3D model (Jmol) Interactive image

NM-2201 (also known as CBL-2201) is an indole-based synthetic cannabinoid that presumably has similar properties to the closely related 5F-PB-22 and NNE1, which are both full agonists and unselectively bind to CB1 and CB2 receptors with low nanomolar affinity.[1][2][3][4]


NM-2201 acts as a full agonist with a binding affinity of 0.332nM at CB1 and 0.732nM at CB2 cannabinoid receptors.[5]

NM-2201 is banned in Sweden[6] and Germany (Anlage II).[7]

See also


  1. A.A. Kondrasenko; E.V. Goncharov; K.P. Dugaev; A.I. Rubaylo (December 2015). "CBL-2201. Report on a new designer drug: Napht-1-yl 1-(5-fluoropentyl)-1H-indole-3-carboxylate". Forensic Science International. 257: 209–213. doi:10.1016/j.forsciint.2015.08.023. PMID 26386336.
  2. "NM-2201". Cayman Chemical. Retrieved 9 July 2015.
  3. Akira Namera; Maho Kawamura; Akihiro Nakamoto; Takeshi Saito; Masataka Nagao (March 2015). "Comprehensive review of the detection methods for synthetic cannabinoids and cathinones". Forensic Toxicology. 33: 175–194. doi:10.1007/s11419-015-0270-0.
  4. V. Shevyrin; V. Melkozerov; A. Nevero; O. Eltsov; A. Baranovsky; Yu. Shafran (September 2014). "Synthetic cannabinoids as designer drugs: New representatives of indol-3-carboxylates series and indazole-3-carboxylates as novel group of cannabinoids. Identification and analytical data". Forensic Science International. 244: 263–275. doi:10.1016/j.forsciint.2014.09.013.
  5. Hess, Cornelius; Schoeder, ClaraT.; Pillaiyar, Thanigaimalai; Madea, Burkhard; Müller, ChristaE. (1 July 2016). "Pharmacological evaluation of synthetic cannabinoids identified as constituents of spice". Forensic Toxicology. 34 (2): 329–343. doi:10.1007/s11419-016-0320-2. ISSN 1860-8965. PMC 4929166Freely accessible. PMID 27429655.
  6. "Cannabinoider föreslås bli klassade som hälsofarlig vara" (in Swedish). Folkhälsomyndigheten. Retrieved 9 July 2015.
  7. "Gesetz über den Verkehr mit Betäubungsmitteln Anlage II". www.gesetze-im-internet.de (in German). Bundesministerium der Justiz und für Verbraucherschutz. Retrieved 24 October 2016.

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