Monoclonal cells are defined as a group of cells produced from a single ancestral cell by repeated cellular replication. Thus they can be said to form a single "clone".[1] The term monoclonal comes from the Ancient Greek monos, meaning "alone" or "single", and klon, denoting "twig".[2]

The process of replication can occur in vivo, or may be stimulated in vitro for laboratory manipulations. The use of the term typically implies that there is some method to distinguish between the cells of the original population from which the single ancestral cell is derived, such as a random genetic alteration, which is inherited by the progeny.

The most common usages of this term are:


  1. "Medterms dictionary definition".
  2. monoclonal. (n.d.) Mosby's Medical Dictionary, 8th edition. (2009). Retrieved August 23 2016 from
This article is issued from Wikipedia - version of the 8/23/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.