Legal status
Legal status
Chemical and physical data
Formula C12H17NO2
Molar mass 207.27 g·mol−1
3D model (Jmol) Interactive image

Mexedrone is a stimulant drug of the cathinone class that has been sold online as a designer drug.[1][2] It is the alpha-methoxy derivative of Mephedrone.


Mexedrone acts as a weak serotonin–norepinephrine–dopamine reuptake inhibitor (SNDRI) with IC50 values of 5289 nM, 8869 nM and 6844 nM, respectively, as well as a weak serotonin releasing agent (SRA) with an EC50 value of 2525 nM.[3]

Mexedrone is illegal in Sweden as of 26. January 2016[4] as well as Japan as of 24. August 2016.[5]

See also


  1. "Mexedrone". New Synthetic Drug Database.
  2. Qian, Zhenhua; Jia, Wei; Li, Tao; Liu, Cuimei; Hua, Zhendong (2016). "Identification and analytical characterization of four synthetic cathinone derivatives iso-4-BMC, β-TH-naphyrone, mexedrone, and 4-MDMC". Drug Testing and Analysis. doi:10.1002/dta.1983. ISSN 1942-7611. PMID 27352812.
  3. McLaughlin, Gavin; Morris, Noreen; Kavanagh, Pierce V.; Power, John D.; Dowling, Geraldine; Twamley, Brendan; O'Brien, John; Talbot, Brian; Walther, Donna; Partilla, John S.; Baumann, Michael H.; Brandt, Simon D. (2016). "Synthesis, characterization and monoamine transporter activity of the new psychoactive substance mexedrone and its N-methoxy positional isomer, N-methoxymephedrone". Drug Testing and Analysis. doi:10.1002/dta.2053. ISSN 1942-7611. PMID 27524685.
  4. "31 nya ämnen kan klassas som narkotika eller hälsofarlig vara" (in Swedish). Folkhälsomyndigheten. November 2015.
  5. "指定薬物一覧" (PDF) (in Japanese). Ministry of Health, Labour and Welfare.

This article is issued from Wikipedia - version of the 8/27/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.