Legal status
Legal status
CAS Number 1616253-26-9
PubChem (CID) 119058037
ChemSpider 30922499
Chemical and physical data
Formula C20H27FN2O3
Molar mass 362.437 g/mol
3D model (Jmol) Interactive image

MMB-2201 (also known as 5F-MMB-PICA, 5F-AMB-PICA, and I-AMB) is a potent indole-3-carboxamide based synthetic cannabinoid,[1] which has been sold as a designer drug and as an active ingredient in synthetic cannabis blends.[2] It was first reported in Russia and Belarus in January 2014, but has since been sold in a number of other countries. It is the indole core analogue of 5F-AMB. Synthetic cannabinoid compounds with an indole-3-carboxamide or indazole-3-carboxamide core bearing a N-1-methoxycarbonyl group with attached isopropyl or t-butyl substituent, have proved to be much more dangerous than older synthetic cannabinoid compounds previously reported, and have been linked to a large number of deaths in Russia, Japan, Europe and the United States.[3][4]


MMB-2201 is illegal in Russia, Belarus and Sweden.[5]

See also


  1. Samuel D Banister; et al. (July 2016). "The pharmacology of valinate and tert-leucinate synthetic cannabinoids 5F-AMBICA, 5F-AMB, 5F-ADB, AMB-FUBINACA, MDMB-FUBINACA, MDMB-CHMICA, and their analogues". ACS Chemical Neuroscience. doi:10.1021/acschemneuro.6b00137.
  2. "MMB-2201". Cayman Chemical. Retrieved 16 July 2015.
  3. V. A. Shevyrin, Yu. Yu. Morzherin, V. P. Melkozerov, A. S. Nevero (July 2014). "New Synthetic Cannabinoid – Methyl 2-{[1-(5-Fluoro-Pentyl)-3-Methyl-1H -Indol-3-Ylcarbonyl]-Amino}Butyrate – as a Designer Drug" (PDF). Chemistry of Heterocyclic Compounds. 50 (4): 583–586. doi:10.1007/s10593-014-1511-6.
  4. Shevyrin V, Melkozerov V, Nevero A, Eltsov O, Shafran Y, Morzherin Y, Lebedev AT (Apr 2015). "Identification and analytical characteristics of synthetic cannabinoids with an indazole-3-carboxamide structure bearing a N-1-methoxycarbonylalkyl group". Analytical and Bioanalytical Chemistry. 407: 6301–15. doi:10.1007/s00216-015-8612-7. PMID 25893797.
  5. "Cannabinoider föreslås bli klassade som hälsofarlig vara". Folkhälsomyndigheten. Retrieved 29 June 2015.

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