Clinical data
ATC code None
Legal status
Legal status
  • Experimental drug
CAS Number 1369764-02-2
PubChem (CID) 56944144
ChemSpider 34500836
Chemical and physical data
Formula C22H20F2N4O2
Molar mass 410.417 g/mol
3D model (Jmol) Interactive image

Lemborexant (INN) (code name E-2006) is a dual antagonist of the orexin OX1 and OX2 receptors which is under development by Eisai for the treatment of insomnia.[1] [2][3] As of December 2014, it is in phase II clinical trials.[4]

See also


  1. Christopher, John A (2014). "Small-molecule antagonists of the orexin receptors". Pharmaceutical Patent Analyst. 3 (6): 625–638. doi:10.4155/ppa.14.46. ISSN 2046-8954.
  2. Cristoph Boss, Catherine Ross (2015). "Recent Trends in Orexin Research – 2010 to 2015". ScienceDirect. doi:10.1016/j.bmcl.2015.05.012.
  3. Boss, Christoph (2014). "Orexin receptor antagonists – a patent review (2010 to August 2014)". Expert Opinion on Therapeutic Patents. 24 (12): 1367–1381. doi:10.1517/13543776.2014.978859. ISSN 1354-3776.
  4. AdisInsight. "Lemborexant". Springer. Retrieved 2015-05-23.
This article is issued from Wikipedia - version of the 10/4/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.