LILRB5

LILRB5
Identifiers
Aliases	LILRB5, CD85C, LIR-8, LIR8, leukocyte immunoglobulin like receptor B5
External IDs	HomoloGene: 134027 GeneCards: LILRB5
Gene ontology Molecular function • transmembrane signaling receptor activity Cellular component • integral component of membrane • membrane Biological process • defense response • cell surface receptor signaling pathway • adaptive immune response • immune system process Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	10990	n/a
Ensembl	n/a	n/a
UniProt	O75023	n/a
RefSeq (mRNA)	NM_001081442 NM_001081443 NM_001304457 NM_006840	n/a
RefSeq (protein)	NP_001074911.1 NP_001074912.1 NP_001291386.1 NP_006831.1	n/a
Location (UCSC)	Chr 19: 54.25 – 54.26 Mb	n/a
PubMed search	[1]	n/a
Wikidata

Leukocyte immunoglobulin-like receptor subfamily B member 5 is a protein that in humans is encoded by the LILRB5 gene.^[2][3]

This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene.^[3]

References

Further reading