Isopropyl nitrite

Isopropyl nitrite
Clinical data
ATC code None
Synonyms Isopropyl alcohol nitrite; nitrous acid, isopropyl ester; 1-methylethyl nitrite; 2-propyl nitrite
CAS Number 541-42-4 YesY
PubChem (CID) 10929
ChemSpider 10466 YesY
ECHA InfoCard 100.007.982
Chemical and physical data
Formula C3H7NO2
Molar mass 89.09
3D model (Jmol) Interactive image
Density 0.8684 g/cm3
Boiling point 40 °C (104 °F)

The chemical compound isopropyl nitrite (or 2-propyl nitrite) is an alkyl nitrite made from isopropanol. It is a clear pale yellow oil.[1]


Isopropyl nitrite is one of the compounds used as poppers, an inhalant drug that induces a brief euphoria. Isopropyl nitrite has largely replaced Isobutyl nitrite in poppers.


Has been associated with Eye Maculopathy visual impairment with central scotomata, associated to bilateral foveal yellow spots and IS/OS junction disruption.[2]


  1. Handbook of Chemistry and Physics, CRC Press, 85th edition
  2. Davies, AJ; Kelly, SP; Naylor, SG; Bhatt, PR; Mathews, JP; Sahni, J; Haslett, R; McKibbin, M (2012). "Adverse ophthalmic reaction in poppers users: case series of 'poppers maculopathy'". Eye (Lond). 26: 1479–86. doi:10.1038/eye.2012.191. PMC 3496104Freely accessible. PMID 23079752.

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