Iotatorquevirus

Iotatorquevirus
Virus classification
Group: Group II (ssDNA)
Family: Anelloviridae
Genus: Iotatorquevirus
Species

Torque Teno Sus Virus

Iotatorquevirus is a recently discovered genus in the new family of Anelloviridae, in group II in the Baltimore classification. It encompasses the two type species of the Torque Teno Sus Virus 1 and 2.

Virology

The virons are small and non enveloped.

The viruses are usually acquired soon after birth and may invade virtually any tissue in the body.[1]

They are widespread in the pig population[2][3]

Genome

The genome is a circular single stranded DNA molecule of negative polarity.

Clinical

Postweaning multisystemic wasting syndrome has been causally associated with porcine circovirus type 2.[4] The Iotatorquevirus have also been linked with this syndrome but a causative role—if one exists—has yet to be established.[5]

References

  1. ↑ Aramouni M, Segalés J, Cortey M, Kekarainen T (2010) Age-related tissue distribution of swine Torque teno sus virus 1 and 2. Vet Microbiol 146(3–4):350–353
  2. ↑ Brink M, Stahl K, Masembe C, Okurut AR, Berg M, Blomstrom AL (2012) First time molecular detection and phylogenetic relationships of torque teno sus virus 1 and 2 in domestic pigs in Uganda: Further evidence for a global distribution. Virol J 9(1):39
  3. ↑ Kekarainen T, Segalés J (2012) Torque Teno Sus Virus in Pigs: an Emerging Pathogen? Transbound Emerg Dis doi: 10.1111/j.1865-1682.2011.01289.x.
  4. ↑ Wallgren P, Belák K, Ehlorsson CJ, Bergström G, Lindberg M, Fossum C, Allan GM, Robertsson JA (2007) Postweaning multisystemic wasting syndrome (PMWS) in Sweden from an exotic to an endemic disease. Vet Q 29(4):122–137
  5. ↑ Nieto D, Aramouni M, Grau-Roma L, Segalés J, Kekarainen T (2011) Dynamics of Torque teno sus virus 1 (TTSuV1) and 2 (TTSuV2) DNA loads in serum of healthy and postweaning multisystemic wasting syndrome (PMWS) affected pigs. Vet Microbiol 152(3–4):284–290

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