He County or Hexian (Chinese: 和县; pinyin: Hé Xiàn) is a district of Anhui Province, People's Republic of China, under the jurisdiction of Ma'anshan. It has a population of 650,000 and an area of 1,412 square kilometres (545 sq mi). The government of He County is located in Liyang Town.
He County has jurisdiction over eleven towns and four townships.
Fossils of Homo erectus, a predecessor of modern humans, were excavated from Longtandong cave on the side of Wanjiashan mountain in Hexian between 1980 and 1981.