Monoclonal antibody
Type Whole antibody
Source Human
Target Beta-amyloid (Aβ40/42)
Clinical data
ATC code none
Legal status
Legal status
  • Investigational
CAS Number 1043556-46-2 N
ChemSpider none
UNII 4DF060P933 YesY
KEGG D09680 YesY
Chemical and physical data
Formula C6496H10072N1740O2024S42
Molar mass 146.3 kg/mol (peptide)
 NYesY (what is this?)  (verify)

Gantenerumab is a monoclonal antibody for the treatment of Alzheimer's disease.[1][2] A phase I clinical trial has been conducted in 2006/07.[3]

Gantenerumab is currently being evaluated in a prodromal Alzheimer's disease population in the Scarlet Road study, a global phase II study of approximately 360 subjects in 100 centers in 15 countries. [4]

One clinical study was stopped on December 19, 2014 after disappointing results.[5]

As of late 2014, Phase III clinical trials are ongoing.[6]


  1. Statement On A Nonproprietary Name Adopted By The Usan Council - Gantenerumab American Medical Association.
  2. International Nonproprietary Names for Pharmaceutical Substances (INN), World Health Organization.
  3. Clinical trial number NCT00531804 for "A Multiple Ascending Dose Study of R1450 in Patients With Alzheimer Disease" at
  6. H. Spreitzer (10 November 2014). "Neue Wirkstoffe – Gantenerumab". Österreichische Apothekerzeitung (in German) (23/2014): 55.

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