Clinical data
ATC code none
CAS Number 515141-51-2
ECHA InfoCard 100.230.542
Chemical and physical data
Formula C25H24ClN3O3S
Molar mass 481.993 g/mol
3D model (Jmol) Interactive image

GW-803430 (GW-3430) is a drug used in scientific research and is a selective non-peptide antagonist at the melanin concentrating hormone receptor MCH1. In animal studies it has anxiolytic, antidepressant and anorectic effects.[1][2]


  1. Chaki S, Kanuma K. Neuropeptide receptors: Novel therapeutic targets for depression and anxiety disorders. Drugs of the Future. 2007;32(9):809.
  2. Gehlert DR, Rasmussen K, Shaw J, Li X, Ardayfio P, Craft L, Coskun T, Zhang HY, Chen Y, Witkin JM (May 2009). "Preclinical evaluation of melanin-concentrating hormone receptor 1 antagonism for the treatment of obesity and depression". The Journal of Pharmacology and Experimental Therapeutics. 329 (2): 429–38. doi:10.1124/jpet.108.143362. PMID 19182070.

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