Clinical data
  • N/A
ATC code None
Legal status
Legal status
  • Investigational
CAS Number 317318-84-6
PubChem (CID) 9934458
ChemSpider 8110086
ChEBI CHEBI:156132
Chemical and physical data
Formula C21H17F4NO3S2
Molar mass 471.488 g/mol
3D model (Jmol) Interactive image

GW0742 (also known as GW610742) is a PPARδ/β agonist[2][3][4] that is investigated for drug use by GlaxoSmithKline.

See also


  1. "Cayman Chemical GW0742". Retrieved 31 Mar 2013.
  2. Smith, S. A.; Monteith, G. R.; Robinson, J. A.; Venkata, N. G.; May, F. J.; Roberts-Thomson, S. J. (2004). "Effect of the peroxisome proliferator-activated receptor ? Activator GW0742 in rat cultured cerebellar granule neurons". Journal of Neuroscience Research. 77 (2): 240–249. doi:10.1002/jnr.20153. PMID 15211590.
  3. Haskova, Z.; Hoang, B.; Luo, G.; Morgan, L. A.; Billin, A. N.; Barone, F. C.; Shearer, B. G.; Barton, M. E.; Kilgore, K. S. (2008). "Modulation of LPS-induced pulmonary neutrophil infiltration and cytokine production by the selective PPARβ/δ ligand GW0742". Inflammation Research. 57 (7): 314–321. doi:10.1007/s00011-007-7157-4. PMID 18622687.
  4. Sznaidman, M. L.; Haffner, C. D.; Maloney, P. R.; Fivush, A.; Chao, E.; Goreham, D.; Sierra, M. L.; Legrumelec, C.; Xu, H. E.; Montana, V. G.; Lambert, M. H.; Willson, T. M.; Oliver, W. R.; Sternbach, D. D. (2003). "Novel selective small molecule agonists for peroxisome proliferator-activated receptor δ (PPARδ)—synthesis and biological activity". Bioorganic & Medicinal Chemistry Letters. 13 (9): 1517. doi:10.1016/S0960-894X(03)00207-5.

This article is issued from Wikipedia - version of the 11/9/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.