Furoxan

Furoxan
Names
IUPAC name
1,2,5-Oxadiazole 2-oxide
Other names
Furazan N-oxide; Furazan 2-oxide
Identifiers
497-27-8 YesY
3D model (Jmol) Interactive image
ChemSpider 4482868 N
MeSH C528141
PubChem 5325374
Properties
C2H2N2O2
Molar mass 86.05 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

Furoxan or 1,2,5-oxadiazole 2-oxide is a heterocycle of the isoxazole family and an amine oxide derivative of furazan. It is a nitric oxide donor.[1] As such, furoxan and its derivatives are actively researched as potential new drugs and insensitive high density explosives.

Furoxanes can be formed by dimerization of nitrile oxides.

References

  1. Clara Cena; Massimo Bertinaria; Donatella Boschi; Marta Giorgis; Alberto Gasco (2006). "Use of the furoxan (1,2,5-oxadiazole 2-oxide) system in the design of new NO-donor antioxidant hybrids" (PDF). Arkivoc (HL-1787GR): 301–309.


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