|Chemical and physical data|
|Molar mass||374.475 g/mol|
|3D model (Jmol)||Interactive image|
Furanylfentanyl (Fu-F) is an opioid analgesic that is an analog of fentanyl and has been sold as a designer drug. It has an ED50 value of 0.02 mg/kg in mice. This makes it approximately five times less potent than fentanyl.
Side effects of fentanyl analogs are similar to those of fentanyl itself, which include itching, nausea and potentially serious respiratory depression, which can be life-threatening. Fentanyl analogs have killed hundreds of people throughout Europe and the former Soviet republics since the most recent resurgence in use began in Estonia in the early 2000s, and novel derivatives continue to appear.
The China connection
According to the DEA, fentanyl and its analog are being mass-produced in clandestine labs in China and are then smuggled into the United States via traditional distribution routes through Mexico. These new variants of fentanyl are manufactured by Chinese chemists in order to circumvent restrictions on sale of fentanyl in the United States.
- List of fentanyl analogues
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- Mohr, Amanda L. A.; Friscia, Melissa; Papsun, Donna; Kacinko, Sherri L.; Buzby, David; Logan, Barry K. (2016). "Analysis of Novel Synthetic Opioids U-47700, U-50488 and Furanyl Fentanyl by LC–MS/MS in Postmortem Casework". Journal of Analytical Toxicology. doi:10.1093/jat/bkw086. PMID 27590036.
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- Armstrong, David (26 April 2016). "Chinese labs modify deadly fentanyl to circumvent ban on sales to US". Stat News.