Fumarate reductase (menaquinone)

Fumarate reductase (menaquinone)
Identifiers
EC number 1.3.5.4
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Fumarate reductase (menaquinone) (EC 1.3.5.4, FRD, menaquinol-fumarate oxidoreductase, succinate dehydrogenase (menaquinone)) is an enzyme with systematic name succinate:menaquinone oxidoreductase.[1][2][3] This enzyme catalyses the following chemical reaction

succinate + a menaquinone fumarate + a menaquinol

The reaction is catalysed in the opposite direction.

References

  1. Iverson, T.M.; Luna-Chavez, C.; Cecchini, G.; Rees, D.C. (1999). "Structure of the Escherichia coli fumarate reductase respiratory complex". Science. 284 (5422): 1961–1966. doi:10.1126/science.284.5422.1961. PMID 10373108.
  2. Cecchini, G.; Schroder, I.; Gunsalus, R.P.; Maklashina, E. (2002). "Succinate dehydrogenase and fumarate reductase from Escherichia coli". Biochim. Biophys. Acta. 1553: 140–157. doi:10.1016/S0005-2728(01)00238-9. PMID 11803023.
  3. Iverson, T.M.; Luna-Chavez, C.; Croal, L.R.; Cecchini, G.; Rees, D.C. (2002). "Crystallographic studies of the Escherichia coli quinol-fumarate reductase with inhibitors bound to the quinol-binding site". J. Biol. Chem. 277 (18): 16124–16130. doi:10.1074/jbc.M200815200. PMID 11850430.
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