Fleischer rings are pigmented rings in the peripheral cornea, resulting from iron deposition in basal epithelial cells, in the form of hemosiderin. They are usually yellowish to dark-brown, and may be complete or broken.
They are named for Bruno Fleischer.
Fleischer rings are indicative of keratoconus, a degenerative corneal condition that causes the cornea to thin and change to a conic shape.
Confusion with Kayser-Fleischer rings
Some confusion exists between Fleischer rings and Kayser-Fleischer rings. Kayser-Fleischer rings are caused by copper deposits, and are indicative of Wilson's disease, whereas Fleischer rings are caused by iron deposits. One example of a medical condition that can present with Fleischer rings is Keratoconus.
Other iron lines:
- "Cornea & External Diseases-Keratoconus Fleischer's Ring". Retrieved 2008-10-24.
- "Definition: Fleischer's ring from Online Medical Dictionary". Retrieved 2008-10-24.
- Fleischer, B (1906). "Über Keratokonus und eigenartige Pigmentbildung in der Kornea". Münchener medizinische Wochenschrift. 53: 625–626.
- Hiratsuka Y, Nakayasu K, Kanai A (2000). "Secondary keratoconus with corneal epithelial iron ring similar to Fleischer's ring". Japanese Journal of Ophthalmology. 44 (4): 381–6. doi:10.1016/S0021-5155(00)00179-9. PMID 10974294.